{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Helm RR"],"funding":["NCRR NIH HHS","NIGMS NIH HHS"],"pagination":["266"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3680055"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14"],"pubmed_abstract":["<h4>Background</h4>Nematostella vectensis, a burrowing sea anemone, has become a popular species for the study of cnidarian development. In previous studies, the expression of a variety of genes has been characterized during N. vectensis development with in situ mRNA hybridization. This has provided detailed spatial resolution and a qualitative perspective on changes in expression. However, little is known about broad transcriptome-level patterns of gene expression through time. Here we examine the expression of N. vectensis genes through the course of development with quantitative RNA-seq. We provide an overview of changes in the transcriptome through development, and examine the maternal to zygotic transition, which has been difficult to investigate with other tools.<h4>Results</h4>We me"],"journal":["BMC genomics"],"pubmed_title":["Characterization of differential transcript abundance through time during Nematostella vectensis development."],"pmcid":["PMC3680055"],"funding_grant_id":["P30RR031153","P30 GM103410"],"pubmed_authors":["Tulin S","Siebert S","Helm RR","Dunn CW","Smith J"],"additional_accession":[]},"is_claimable":false,"name":"Characterization of differential transcript abundance through time during Nematostella vectensis development.","description":"<h4>Background</h4>Nematostella vectensis, a burrowing sea anemone, has become a popular species for the study of cnidarian development. In previous studies, the expression of a variety of genes has been characterized during N. vectensis development with in situ mRNA hybridization. This has provided detailed spatial resolution and a qualitative perspective on changes in expression. However, little is known about broad transcriptome-level patterns of gene expression through time. Here we examine the expression of N. vectensis genes through the course of development with quantitative RNA-seq. We provide an overview of changes in the transcriptome through development, and examine the maternal to zygotic transition, which has been difficult to investigate with other tools.<h4>Results</h4>We me","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Apr","modification":"2026-05-30T09:57:55.782Z","creation":"2026-04-08T06:58:29.656Z"},"accession":"S-EPMC3680055","cross_references":{"pubmed":["23601508"],"doi":["10.1186/1471-2164-14-266"]}}