biostudies-literatureHelm RRNCRR NIH HHSNIGMS NIH HHS266https://www.ebi.ac.uk/biostudies/studies/S-EPMC3680055biostudies-literatureUnknown14<h4>Background</h4>Nematostella vectensis, a burrowing sea anemone, has become a popular species for the study of cnidarian development. In previous studies, the expression of a variety of genes has been characterized during N. vectensis development with in situ mRNA hybridization. This has provided detailed spatial resolution and a qualitative perspective on changes in expression. However, little is known about broad transcriptome-level patterns of gene expression through time. Here we examine the expression of N. vectensis genes through the course of development with quantitative RNA-seq. We provide an overview of changes in the transcriptome through development, and examine the maternal to zygotic transition, which has been difficult to investigate with other tools.<h4>Results</h4>We meBMC genomicsCharacterization of differential transcript abundance through time during Nematostella vectensis development.PMC3680055P30RR031153P30 GM103410Tulin SSiebert SHelm RRDunn CWSmith JfalseCharacterization of differential transcript abundance through time during Nematostella vectensis development.<h4>Background</h4>Nematostella vectensis, a burrowing sea anemone, has become a popular species for the study of cnidarian development. In previous studies, the expression of a variety of genes has been characterized during N. vectensis development with in situ mRNA hybridization. This has provided detailed spatial resolution and a qualitative perspective on changes in expression. However, little is known about broad transcriptome-level patterns of gene expression through time. Here we examine the expression of N. vectensis genes through the course of development with quantitative RNA-seq. We provide an overview of changes in the transcriptome through development, and examine the maternal to zygotic transition, which has been difficult to investigate with other tools.<h4>Results</h4>We me2013-01-01T00:00:00Z2013 Apr2026-05-30T09:57:55.782Z2026-04-08T06:58:29.656ZS-EPMC36800552360150810.1186/1471-2164-14-266