biostudies-literatureUnknown8(6)Stenrod MThere is widespread use of chemical amendments to meet the demands for increased productivity in agriculture. Potentially toxic compounds, single or in mixtures, are added to the soil medium on a regular basis, while the ecotoxicological risk assessment procedures mainly follow a chemical by chemical approach. Picoxystrobin is a fungicide that has caused concern due to studies showing potentially detrimental effects to soil fauna (earthworms), while negative effects on soil microbial activities (nitrification, respiration) are shown to be transient. Potential mixture situations with nonylphenol, a chemical frequently occurring as a contaminant in sewage sludge used for land application, infer a need to explore whether these chemicals in mixture could alter the potential effects of picoxystPloS onee66989https://www.ebi.ac.uk/biostudies/studies/S-EPMC3688581biostudies-literatureEffects of picoxystrobin and 4-n-nonylphenol on soil microbial community structure and respiration activity.PMC3688581Norli HRStenrod MEklo OMKlemsdal SSfalseEffects of picoxystrobin and 4-n-nonylphenol on soil microbial community structure and respiration activity.There is widespread use of chemical amendments to meet the demands for increased productivity in agriculture. Potentially toxic compounds, single or in mixtures, are added to the soil medium on a regular basis, while the ecotoxicological risk assessment procedures mainly follow a chemical by chemical approach. Picoxystrobin is a fungicide that has caused concern due to studies showing potentially detrimental effects to soil fauna (earthworms), while negative effects on soil microbial activities (nitrification, respiration) are shown to be transient. Potential mixture situations with nonylphenol, a chemical frequently occurring as a contaminant in sewage sludge used for land application, infer a need to explore whether these chemicals in mixture could alter the potential effects of picoxyst2013-01-01T00:00:00Z20132025-04-19T17:10:21.408Z2019-03-26T23:14:48ZS-EPMC36885812381897110.1371/journal.pone.0066989