{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Strohm EM"],"funding":["Canadian Institutes of Health Research"],"pagination":["59-67"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3699781"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["105(1)"],"pubmed_abstract":["A method that can rapidly quantify variations in the morphology of single red blood cells (RBCs) using light and sound is presented. When irradiated with a laser pulse, an RBC absorbs the optical energy and emits an ultrasonic pressure wave called a photoacoustic wave. The power spectrum of the resulting photoacoustic wave contains distinctive features that can be used to identify the RBC size and morphology. When particles 5-10 μm in diameter (such as RBCs) are probed with high-frequency photoacoustics, unique periodically varying minima and maxima occur throughout the photoacoustic signal power spectrum at frequencies >100 MHz. The location and distance between spectral minima scale with the size and morphology of the RBC; these shifts can be used to quantify small changes in the morphol"],"journal":["Biophysical journal"],"pubmed_title":["Probing red blood cell morphology using high-frequency photoacoustics."],"pmcid":["PMC3699781"],"funding_grant_id":["CCI 1117964"],"pubmed_authors":["Strohm EM","Kolios MC","Berndl ES"],"additional_accession":[]},"is_claimable":false,"name":"Probing red blood cell morphology using high-frequency photoacoustics.","description":"A method that can rapidly quantify variations in the morphology of single red blood cells (RBCs) using light and sound is presented. When irradiated with a laser pulse, an RBC absorbs the optical energy and emits an ultrasonic pressure wave called a photoacoustic wave. The power spectrum of the resulting photoacoustic wave contains distinctive features that can be used to identify the RBC size and morphology. When particles 5-10 μm in diameter (such as RBCs) are probed with high-frequency photoacoustics, unique periodically varying minima and maxima occur throughout the photoacoustic signal power spectrum at frequencies >100 MHz. The location and distance between spectral minima scale with the size and morphology of the RBC; these shifts can be used to quantify small changes in the morphol","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Jul","modification":"2026-06-29T03:15:38.315Z","creation":"2019-03-27T01:12:25Z"},"accession":"S-EPMC3699781","cross_references":{"pubmed":["23823224"],"doi":["10.1016/j.bpj.2013.05.037"]}}