biostudies-literatureUnknown8(7)Brown TThe impact of disease outbreaks on coral physiology represents an increasing concern for the fitness and resilience of reef ecosystems. Predicting the tolerance of corals to disease relies on an understanding of the coral immune response to pathogenic interactions. This study explored the transcriptional response of two putative immune genes (c3 and c-type lectin) and one stress response gene (hsp70) in the reef building coral, Acropora millepora challenged for 48 hours with bacterial strains, Vibrio coralliilyticus and Alteromonas sp. at concentrations of 10(6) cells ml(-1). Coral fragments challenged with V. coralliilyticus appeared healthy while fragments challenged with Alteromonas sp. showed signs of tissue lesions after 48 hr. Coral-associated bacterial community profiles assessed usPloS onee67246https://www.ebi.ac.uk/biostudies/studies/S-EPMC3701546biostudies-literatureTranscriptional activation of c3 and hsp70 as part of the immune response of Acropora millepora to bacterial challenges.PMC3701546Rodriguez-Lanetty MBourne DBrown TfalseTranscriptional activation of c3 and hsp70 as part of the immune response of Acropora millepora to bacterial challenges.The impact of disease outbreaks on coral physiology represents an increasing concern for the fitness and resilience of reef ecosystems. Predicting the tolerance of corals to disease relies on an understanding of the coral immune response to pathogenic interactions. This study explored the transcriptional response of two putative immune genes (c3 and c-type lectin) and one stress response gene (hsp70) in the reef building coral, Acropora millepora challenged for 48 hours with bacterial strains, Vibrio coralliilyticus and Alteromonas sp. at concentrations of 10(6) cells ml(-1). Coral fragments challenged with V. coralliilyticus appeared healthy while fragments challenged with Alteromonas sp. showed signs of tissue lesions after 48 hr. Coral-associated bacterial community profiles assessed us2013-01-01T00:00:00Z20132026-04-08T16:44:03.817Z2019-03-26T23:15:04ZS-EPMC37015462386175410.1371/journal.pone.0067246