biostudies-literatureUnknown15(8)Cinca J<h4>Aims</h4>Intraventricular conduction defects (IVCDs) can impair prognosis of heart failure (HF), but their specific impact is not well established. This study aimed to analyse the clinical profile and outcomes of HF patients with LBBB, right bundle branch block (RBBB), left anterior fascicular block (LAFB), and no IVCDs.<h4>Methods and results</h4>Clinical variables and outcomes after a median follow-up of 21 months were analysed in 1762 patients with chronic HF and LBBB (n = 532), RBBB (n = 134), LAFB (n = 154), and no IVCDs (n = 942). LBBB was associated with more marked LV dilation, depressed LVEF, and mitral valve regurgitation. Patients with RBBB presented overt signs of congestive HF and depressed right ventricular motion. The LAFB group presented intermediate clinical characteriEuropean journal of heart failure877-84https://www.ebi.ac.uk/biostudies/studies/S-EPMC3721573biostudies-literatureDifferential clinical characteristics and prognosis of intraventricular conduction defects in patients with chronic heart failure.PMC3721573Carrillo ACarreras FGarcia-Pavia PVila VPerez-Serrano MGonzalez-Juanatey JRReinares LAguilar SAlonso MDaga BBorras XVila ITello de Meneses RHevia SRozas MPerez-Villacastin JFernandez-Hernandez LDelgado JLago FCerain JVillalonga MVicente-Hernandez MSancho-Jaldon MSeoane AHernandez-Vicente NCinca JArribas FMartinez-Dolz LDomingo MLeal Del Ojo JRodriguez-Cristobal JCobos MGarcia-Acuna JParadina MGarcia-Touchard AGarcia-Lareo MFlox APerez-Castellano NPerez-Orcero ASan Vicente LBordiu EOrosa PEscribano PDe la Puerta IAizpurua MCasanova JGarrido IEscolar VSevillano RPadro JRibas NSilva LVerdu JMPastor-Perez FJFernandez-Lozano ISanchez-Sanchez VFernandez-Pinilla CTroncoso APerez-Navarro AHove-Madsen LTorres GAguero JSalvador ARivera MFiol CPedrajas JDelgado JFPuig TVillagomez DRubio JBandin MDiaz-Retamino EGiraldes ABartolome DGrau-Sepulveda AManzon PCabau JPortoles MAramburu OMoure MSaenz de la Calzada CMarquez JLear PVBerruezo AGrigorian-Shamagian LOtero-Santiago FFerrero AHernandez-Martin IGarcia-Gonzalez CCasacuberta JViles DRosello-Lleti Einvestigators of the Spanish Heart Failure Network (REDINSCOR)Cabeza PAlvarez de Arcaya Vicente AJimenez-Cervantes DMoreno JMartell NBravo CPavon RPatino RMont LGrau-Amoros JValdes MPlanas-Comes FPlanas-Ayma FGonzalez-Rubio LBarta LCamacho FAlonso-Pulpon LJimenez Lopez-Guarch CGamaza SGomez-Garre DGarcia-Medina DRoig EOrtega ACalle-Perez GSanz-Girgas EBatlle MGomez-Otero IFernandez-Rivero RSalguero RPastor-Torres LGomez-Bueno MSorribes JLaguna EPascual-Figal DASanchez-Mas JAlmenar LPericas PPascual-Figal DBischofberger COtero-Ravina FBover RZayas REiras SAlvarez-Garcia JToran PLagares MVarela AGarcia-Rey SMunoz-Pacheco PRuiz-Cano JMerce JMartinez RRodino Janeiro BKGuerra JMVazquez-Mosquera MPerez-Villa FVinolas XLopez-Benitez JTornel PArana RHerrero-Melechon JPinol EPueo EMontero JUrena ICubero JSegovia JJorge EAvila MValdovinos PVazquez ROtero EAlguacil FArias JWorner FSalgado ABrugada JGarcia-Alberola AMena AMarco JMendez AGarcia-Quintanilla JMarante MLopez-Pareja NBayes de Luna AFernandez-Cruz ACortes RDominguez-De Pablos GCano LFernandez-Palacin ABardaji APedregal JMinano FCalle LfalseDifferential clinical characteristics and prognosis of intraventricular conduction defects in patients with chronic heart failure.<h4>Aims</h4>Intraventricular conduction defects (IVCDs) can impair prognosis of heart failure (HF), but their specific impact is not well established. This study aimed to analyse the clinical profile and outcomes of HF patients with LBBB, right bundle branch block (RBBB), left anterior fascicular block (LAFB), and no IVCDs.<h4>Methods and results</h4>Clinical variables and outcomes after a median follow-up of 21 months were analysed in 1762 patients with chronic HF and LBBB (n = 532), RBBB (n = 134), LAFB (n = 154), and no IVCDs (n = 942). LBBB was associated with more marked LV dilation, depressed LVEF, and mitral valve regurgitation. Patients with RBBB presented overt signs of congestive HF and depressed right ventricular motion. The LAFB group presented intermediate clinical characteri2013-01-01T00:00:00Z2013 Aug2025-04-26T20:33:00.326Z2019-03-27T01:13:35ZS-EPMC37215732351209710.1093/eurjhf/hft042