{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["McLaren PJ"],"funding":["Intramural NIH HHS","Howard Hughes Medical Institute","NIDA NIH HHS","NIAID NIH HHS","NHLBI NIH HHS","PHS HHS"],"pagination":["e1003515"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3723635"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(7)"],"pubmed_abstract":["Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, identifying common genetic influences on viral control and disease course. Similarly, common genetic correlates of acquisition of HIV-1 after exposure have been interrogated using GWAS, although in generally small samples. Under the auspices of the International Collaboration for the Genomics of HIV, we have combined the genome-wide single nucleotide polymorphism (SNP) data collected by 25 cohorts, studies, or institutions on HIV-1 infected individuals and compared them to carefully matched population-level data sets (a list of all collaborators appears in Note S1 in Text S1). After imputation using the 1,000 Genomes Project reference panel, we tested approximately 8 million common DNA varian"],"journal":["PLoS pathogens"],"pubmed_title":["Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls."],"pmcid":["PMC3723635"],"funding_grant_id":["T32 AI007140","HHSN26120080001E","P01 AI057005","R37 AI047734","U01 DA036297","UM1 AI069496","R01 DA012568","R01 HL087676"],"pubmed_authors":["Walker BD","van Manen D","Goldstein DB","McLaren PJ","Herbeck JT","Zagury JF","Ripke S","Cossarizza A","Haas D","Theodorou I","Poli G","Wolinsky S","Schuitemaker H","Fellay J","Mullins JI","O'Brien SJ","de Bakker PI","Qi Y","De Luca A","Delaneau O","Martinez-Picado J","Vannberg F","Kathiresan S","Goedert JJ","Rucart P","Winkler CA","Shea PR","Coulonges C","Carrington M","Meyer L","Obel N","Miro JM","Lambotte O","Weintrob A","Kirk GD","Pereyra F","Mallal S","Plummer FA","Telenti A","Luo M","Sandhu MS","Buchbinder S","Dalmau J","van den Berg L","Veldink J","Deeks SG"],"additional_accession":[]},"is_claimable":false,"name":"Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls.","description":"Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, identifying common genetic influences on viral control and disease course. Similarly, common genetic correlates of acquisition of HIV-1 after exposure have been interrogated using GWAS, although in generally small samples. Under the auspices of the International Collaboration for the Genomics of HIV, we have combined the genome-wide single nucleotide polymorphism (SNP) data collected by 25 cohorts, studies, or institutions on HIV-1 infected individuals and compared them to carefully matched population-level data sets (a list of all collaborators appears in Note S1 in Text S1). After imputation using the 1,000 Genomes Project reference panel, we tested approximately 8 million common DNA varian","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013","modification":"2026-05-05T18:30:33.555Z","creation":"2026-04-07T21:47:06.733Z"},"accession":"S-EPMC3723635","cross_references":{"pubmed":["23935489"],"doi":["10.1371/journal.ppat.1003515"]}}