biostudies-literatureKumar NNNIGMS NIH HHS9608-11https://www.ebi.ac.uk/biostudies/studies/S-EPMC3763736biostudies-literatureUnknown135(26)Enantiopure alkaloid mimics are synthesized via high yielding intramolecular cycloadditions of photogenerated azaxylylenes tethered to pyrroles, with further growth of molecular complexity via post-photochemical transformations of primary photoproducts. This expeditious access to structurally unprecedented polyheterocyclic cores is being developed in the context of diversity-oriented synthesis, as the modular design allows for rapid "pre-assembly" of diverse photoprecursors from simple building blocks/diversity inputs.Journal of the American Chemical SocietyPhotoassisted synthesis of enantiopure alkaloid mimics possessing unprecedented polyheterocyclic cores.PMC3763736GM-093930R15 GM093930Kumar NNMukhina OAKutateladze AGfalsePhotoassisted synthesis of enantiopure alkaloid mimics possessing unprecedented polyheterocyclic cores.Enantiopure alkaloid mimics are synthesized via high yielding intramolecular cycloadditions of photogenerated azaxylylenes tethered to pyrroles, with further growth of molecular complexity via post-photochemical transformations of primary photoproducts. This expeditious access to structurally unprecedented polyheterocyclic cores is being developed in the context of diversity-oriented synthesis, as the modular design allows for rapid "pre-assembly" of diverse photoprecursors from simple building blocks/diversity inputs.2013-01-01T00:00:00Z2013 Jul2025-04-04T09:40:45.483Z2019-03-26T23:30:06ZS-EPMC37637362378984110.1021/ja4042109