{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rajpara N"],"funding":["FDA HHS","NIMHD NIH HHS","PHS HHS"],"pagination":["e76200"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3781066"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8(9)"],"pubmed_abstract":["<h4>Background</h4>Vibrio cholerae non-O1/ non-O139 serogroups have been reported to cause sporadic diarrhoea in humans. Cholera toxins have been mostly implicated for hypersecretion of ions and water into the small intestine. Though most of the V. cholerae non-O1/ non-O139 strains lack these cholera toxins, several other innate virulence factors contribute towards their pathogenicity. The environmental isolates may thus act as reservoirs for potential spreading of these virulence genes in the natural environment which may cause the emergence of epidemic-causing organisms.<h4>Results</h4>The environmental isolates of vibrios were obtained from water samples, zooplanktons and phytoplanktons, from a village pond in Gandhinagar, Gujarat, India. They were confirmed as Vibrio cholerae non-O1/ n"],"journal":["PloS one"],"pubmed_title":["Synergistic effect of various virulence factors leading to high toxicity of environmental V. cholerae non-O1/ non-O139 isolates lacking ctx gene : comparative study with clinical strains."],"pmcid":["PMC3781066"],"funding_grant_id":["BT/PR/11634/INF/22/104/2008","F/815/2011-ECD-II","GSBTM/MD/PROJECTS/SSA/3386/2012-13"],"pubmed_authors":["Nag D","Singh AK","Mohanty P","Sinha R","Rajpara N","Kushwaha Bhardwaj A","Koley H","Singh R","Vinothkumar K"],"additional_accession":[]},"is_claimable":false,"name":"Synergistic effect of various virulence factors leading to high toxicity of environmental V. cholerae non-O1/ non-O139 isolates lacking ctx gene : comparative study with clinical strains.","description":"<h4>Background</h4>Vibrio cholerae non-O1/ non-O139 serogroups have been reported to cause sporadic diarrhoea in humans. Cholera toxins have been mostly implicated for hypersecretion of ions and water into the small intestine. Though most of the V. cholerae non-O1/ non-O139 strains lack these cholera toxins, several other innate virulence factors contribute towards their pathogenicity. The environmental isolates may thus act as reservoirs for potential spreading of these virulence genes in the natural environment which may cause the emergence of epidemic-causing organisms.<h4>Results</h4>The environmental isolates of vibrios were obtained from water samples, zooplanktons and phytoplanktons, from a village pond in Gandhinagar, Gujarat, India. They were confirmed as Vibrio cholerae non-O1/ n","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013","modification":"2025-04-04T20:52:09.492Z","creation":"2019-03-27T01:16:26Z"},"accession":"S-EPMC3781066","cross_references":{"pubmed":["24086707"],"doi":["10.1371/journal.pone.0076200"]}}