{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Darrow LA"],"funding":["NIEHS NIH HHS"],"pagination":["1207-13"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3801459"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["121(10)"],"pubmed_abstract":["<h4>Background</h4>Previous research suggests perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) may be associated with adverse pregnancy outcomes.<h4>Objective</h4>We conducted a population-based study of PFOA and PFOS and birth outcomes from 2005 through 2010 in a Mid-Ohio Valley community exposed to high levels of PFOA through drinking-water contamination.<h4>Methods</h4>Women provided serum for PFOA and PFOS measurement in 2005-2006 and reported reproductive histories in subsequent follow-up interviews. Reported singleton live births among 1,330 women after 1 January 2005 were linked to birth records (n = 1,630) to identify the outcomes of preterm birth (< 37 weeks gestation), pregnancy-induced hypertension, low birth weight (< 2,500 g), and birth weight (grams) among f"],"journal":["Environmental health perspectives"],"pubmed_title":["Serum perfluorooctanoic acid and perfluorooctane sulfonate concentrations in relation to birth outcomes in the Mid-Ohio Valley, 2005-2010."],"pmcid":["PMC3801459"],"funding_grant_id":["K01 ES019156","K01ES019156"],"pubmed_authors":["Darrow LA","Steenland K","Stein CR"],"additional_accession":[]},"is_claimable":false,"name":"Serum perfluorooctanoic acid and perfluorooctane sulfonate concentrations in relation to birth outcomes in the Mid-Ohio Valley, 2005-2010.","description":"<h4>Background</h4>Previous research suggests perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) may be associated with adverse pregnancy outcomes.<h4>Objective</h4>We conducted a population-based study of PFOA and PFOS and birth outcomes from 2005 through 2010 in a Mid-Ohio Valley community exposed to high levels of PFOA through drinking-water contamination.<h4>Methods</h4>Women provided serum for PFOA and PFOS measurement in 2005-2006 and reported reproductive histories in subsequent follow-up interviews. Reported singleton live births among 1,330 women after 1 January 2005 were linked to birth records (n = 1,630) to identify the outcomes of preterm birth (< 37 weeks gestation), pregnancy-induced hypertension, low birth weight (< 2,500 g), and birth weight (grams) among f","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Oct","modification":"2025-04-25T22:57:00.517Z","creation":"2019-03-27T01:17:24Z"},"accession":"S-EPMC3801459","cross_references":{"pubmed":["23838280"],"doi":["10.1289/ehp.1206372"]}}