{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Molander GA"],"funding":["NCRR NIH HHS","NIGMS NIH HHS","PHS HHS"],"pagination":["5052-5"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3820111"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(19)"],"pubmed_abstract":["The synthesis of β,γ-alkynyl esters and amides using air-stable potassium alkynyltrifluoroborates as nucleophilic partners in a mild Suzuki-Miyaura cross-coupling reaction has been achieved. Propargyl esters and amides were obtained in high yields using a low catalyst loading, and the substrate scope of the reaction has been significantly improved over previous methods."],"journal":["Organic letters"],"pubmed_title":["Pd-catalyzed alkynylation of 2-chloroacetates and 2-chloroacetamides with potassium alkynyltrifluoroborates."],"pmcid":["PMC3820111"],"funding_grant_id":["R01 GM035249","S10 RR016640","R01 035249"],"pubmed_authors":["Traister KM","Molander GA"],"additional_accession":[]},"is_claimable":false,"name":"Pd-catalyzed alkynylation of 2-chloroacetates and 2-chloroacetamides with potassium alkynyltrifluoroborates.","description":"The synthesis of β,γ-alkynyl esters and amides using air-stable potassium alkynyltrifluoroborates as nucleophilic partners in a mild Suzuki-Miyaura cross-coupling reaction has been achieved. Propargyl esters and amides were obtained in high yields using a low catalyst loading, and the substrate scope of the reaction has been significantly improved over previous methods.","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Oct","modification":"2025-04-04T07:25:02.298Z","creation":"2019-03-27T03:08:11Z"},"accession":"S-EPMC3820111","cross_references":{"pubmed":["24040828"],"doi":["10.1021/ol402391z"]}}