{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Liu G"],"pubmed_abstract":["<h4>Background</h4>Streptococcus agalactiae, also referred to as Group B Streptococcus (GBS), is a frequent resident of the rectovaginal tract in humans, and a major cause of neonatal infection. In addition, S. agalactiae is a known fish pathogen, which compromises food safety and represents a zoonotic hazard. The complete genome sequence of the piscine S. agalactiae isolate GD201008-001 was compared with 14 other piscine, human and bovine strains to explore their virulence determinants, evolutionary relationships and the genetic basis of host tropism in S. agalactiae.<h4>Results</h4>The pan-genome of S. agalactiae is open and its size increases with the addition of newly sequenced genomes. The core genes shared by all isolates account for 50 ~ 70% of any single genome. The Chinese piscine"],"journal":["BMC genomics"],"pagination":["775"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3831827"],"repository":["biostudies-literature"],"pubmed_title":["Comparative genomics analysis of Streptococcus agalactiae reveals that isolates from cultured tilapia in China are closely related to the human strain A909."],"pmcid":["PMC3831827"],"pubmed_authors":["Zhang W","Lu C","Liu G"],"additional_accession":[]},"is_claimable":false,"name":"Comparative genomics analysis of Streptococcus agalactiae reveals that isolates from cultured tilapia in China are closely related to the human strain A909.","description":"<h4>Background</h4>Streptococcus agalactiae, also referred to as Group B Streptococcus (GBS), is a frequent resident of the rectovaginal tract in humans, and a major cause of neonatal infection. In addition, S. agalactiae is a known fish pathogen, which compromises food safety and represents a zoonotic hazard. The complete genome sequence of the piscine S. agalactiae isolate GD201008-001 was compared with 14 other piscine, human and bovine strains to explore their virulence determinants, evolutionary relationships and the genetic basis of host tropism in S. agalactiae.<h4>Results</h4>The pan-genome of S. agalactiae is open and its size increases with the addition of newly sequenced genomes. The core genes shared by all isolates account for 50 ~ 70% of any single genome. The Chinese piscine","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Nov","modification":"2026-05-01T15:30:01.966Z","creation":"2019-03-27T03:08:46Z"},"accession":"S-EPMC3831827","cross_references":{"pubmed":["24215651"],"doi":["10.1186/1471-2164-14-775"]}}