biostudies-literatureChung WJNIGMS NIH HHS10052-5https://www.ebi.ac.uk/biostudies/studies/S-EPMC3835569biostudies-literatureUnknown52(38)Magnificent seven: The chlorosulfolipid mytilipin A was synthesized in racemic form in seven steps and in enantioenriched form in eight steps. Key transformations include a highly diastereoselective bromoallylation of a sensitive α,β-dichloroaldehyde, a kinetic resolution of a vinyl epoxide, a convergent and highly Z-selective alkene cross-metathesis, and a chemoselective and diastereoselective dichlorination of a complex diene.Angewandte Chemie (International ed. in English)A synthesis of the chlorosulfolipid mytilipin A via a longest linear sequence of seven steps.PMC3835569R01 GM086483Chung WJBedke DKCarlson JSVanderwal CDfalseA synthesis of the chlorosulfolipid mytilipin A via a longest linear sequence of seven steps.Magnificent seven: The chlorosulfolipid mytilipin A was synthesized in racemic form in seven steps and in enantioenriched form in eight steps. Key transformations include a highly diastereoselective bromoallylation of a sensitive α,β-dichloroaldehyde, a kinetic resolution of a vinyl epoxide, a convergent and highly Z-selective alkene cross-metathesis, and a chemoselective and diastereoselective dichlorination of a complex diene.2013-01-01T00:00:00Z2013 Sep2025-04-04T12:26:43.144Z2019-03-27T03:09:02ZS-EPMC38355692392959610.1002/anie.201304565