biostudies-literature00510Xie YNIGMS NIH HHS625-8https://www.ebi.ac.uk/biostudies/studies/S-EPMC3857712biostudies-literatureUnknown52(2)Complexity from simplicity: polycyclic ethers are synthesized by cascade reactions involving the use of epoxides as electrophilic traps in the transposition of allylic alcohols. Stereogenic centers are created by functionalizing prochiral sites under thermodynamic control, and remote stereoinduction can be achieved through the use of ketones as conduits.Angewandte Chemie (International ed. in English)Cascade approach to stereoselective polycyclic ether formation: epoxides as trapping agents in the transposition of allylic alcohols.PMC3857712P50 GM067082P50-GM06082Xie YFloreancig PE51falseCascade approach to stereoselective polycyclic ether formation: epoxides as trapping agents in the transposition of allylic alcohols.Complexity from simplicity: polycyclic ethers are synthesized by cascade reactions involving the use of epoxides as electrophilic traps in the transposition of allylic alcohols. Stereogenic centers are created by functionalizing prochiral sites under thermodynamic control, and remote stereoinduction can be achieved through the use of ketones as conduits.2013-01-01T00:00:00Z2013 Jan2020-10-29T11:46:22Z2019-03-27T01:18:15ZS-EPMC38577122317271710.1002/anie.201208132