{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10"],"submitter":["Bruss H"],"pubmed_abstract":["Synthetic investigations towards the structurally complex and highly decorated framework of B-seco limonoid natural products by means of a [3,3]-sigmatropic rearrangement are described. Detailed model studies reveal, that an Ireland-Claisen rearrangement can be employed to construct the central C9-C10 bond thereby giving access to the B-seco limonoid scaffold. However, application of the developed strategy ended up failing in more complex and sterically demanding systems."],"journal":["Beilstein journal of organic chemistry"],"pagination":["194-208"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3943702"],"repository":["biostudies-literature"],"pubmed_title":["Synthesis of the B-seco limonoid core scaffold."],"pmcid":["PMC3943702"],"pubmed_authors":["Waldmann H","Bruss H","Schuster H","Martinez R","Antonchick AP","Kaiser M"],"additional_accession":[]},"is_claimable":false,"name":"Synthesis of the B-seco limonoid core scaffold.","description":"Synthetic investigations towards the structurally complex and highly decorated framework of B-seco limonoid natural products by means of a [3,3]-sigmatropic rearrangement are described. Detailed model studies reveal, that an Ireland-Claisen rearrangement can be employed to construct the central C9-C10 bond thereby giving access to the B-seco limonoid scaffold. However, application of the developed strategy ended up failing in more complex and sterically demanding systems.","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014","modification":"2025-04-04T14:14:29.334Z","creation":"2019-03-27T01:22:44Z"},"accession":"S-EPMC3943702","cross_references":{"pubmed":["24605139"],"doi":["10.3762/bjoc.10.15"]}}