biostudies-literaturePope WHHoward Hughes Medical InstituteNIMHD NIH HHS2461-80https://www.ebi.ac.uk/biostudies/studies/S-EPMC3958112biostudies-literatureUnknown88(5)<h4>Unlabelled</h4>Genomic analysis of a large set of phages infecting the common host Mycobacterium smegmatis mc(2)155 shows that they span considerable genetic diversity. There are more than 20 distinct types that lack nucleotide similarity with each other, and there is considerable diversity within most of the groups. Three newly isolated temperate mycobacteriophages, Bongo, PegLeg, and Rey, constitute a new group (cluster M), with the closely related phages Bongo and PegLeg forming subcluster M1 and the more distantly related Rey forming subcluster M2. The cluster M mycobacteriophages have siphoviral morphologies with unusually long tails, are homoimmune, and have larger than average genomes (80.2 to 83.7 kbp). They exhibit a variety of features not previously described in other mycobaJournal of virologyCluster M mycobacteriophages Bongo, PegLeg, and Rey with unusually large repertoires of tRNA isotypes.PMC39581125200696152006944P20 MD006144Boyle MMDeJong RJBroussard GWZhang DCresawn SGRussell DAOlm MRSanders ERDeng LCooper SRubin MRHatfull GFShaffer CDBaird MCornely KAWherley JBowman CAPeebles CLDelesalle VAHughes LESchoer MPage STChow TMeier CGPope WHHendrix RWDunbar DHartzog GAWeston Hafer KYuan HClase KLFerreira CMJacobs-Sera DEdgington NPMonti DLIpapo KVazquez EHatherill JRAnders KRKrukonis GPRinehart CAfalseCluster M mycobacteriophages Bongo, PegLeg, and Rey with unusually large repertoires of tRNA isotypes.<h4>Unlabelled</h4>Genomic analysis of a large set of phages infecting the common host Mycobacterium smegmatis mc(2)155 shows that they span considerable genetic diversity. There are more than 20 distinct types that lack nucleotide similarity with each other, and there is considerable diversity within most of the groups. Three newly isolated temperate mycobacteriophages, Bongo, PegLeg, and Rey, constitute a new group (cluster M), with the closely related phages Bongo and PegLeg forming subcluster M1 and the more distantly related Rey forming subcluster M2. The cluster M mycobacteriophages have siphoviral morphologies with unusually long tails, are homoimmune, and have larger than average genomes (80.2 to 83.7 kbp). They exhibit a variety of features not previously described in other mycoba2014-01-01T00:00:00Z2014 Mar2025-04-26T09:14:13.958Z2019-03-27T01:23:35ZS-EPMC39581122433531410.1128/JVI.03363-1310.1128/jvi.03363-13