biostudies-literatureBlake JANHGRI NIH HHSNCI NIH HHSNIH HHSD810-7https://www.ebi.ac.uk/biostudies/studies/S-EPMC3964950biostudies-literatureUnknown42(Database issue)The Mouse Genome Database (MGD) (http://www.informatics.jax.org) is the community model organism database resource for the laboratory mouse, a premier animal model for the study of genetic and genomic systems relevant to human biology and disease. MGD maintains a comprehensive catalog of genes, functional RNAs and other genome features as well as heritable phenotypes and quantitative trait loci. The genome feature catalog is generated by the integration of computational and manual genome annotations generated by NCBI, Ensembl and Vega/HAVANA. MGD curates and maintains the comprehensive listing of functional annotations for mouse genes using the Gene Ontology, and MGD curates and integrates comprehensive phenotype annotations including associations of mouse models with human diseases. Recent improvements include integration of the latest mouse genome build (GRCm38), improved access to comparative and functional annotations for mouse genes with expanded representation of comparative vertebrate genomes and new loads of phenotype data from high-throughput phenotyping projects. All MGD resources are freely available to the research community.Nucleic acids researchThe Mouse Genome Database: integration of and access to knowledge about the laboratory mouse.PMC3964950U41 HG000330P30 CA034196OD011190HG000330Motenko HMouse Genome Database GroupBult CJZhu YBello SSitnikov DBerghout JWashburn LDolan MKnowlton MDene HTomczuk MRecla JMCorbani LButler NGiannatto SLBlake JADrabkin HJNi LLewis JBeal JHale PSmith CEppig JTRichardson JEMcAndrews MOnda HRichards-Smith BL KKadin JAReed DfalseThe Mouse Genome Database: integration of and access to knowledge about the laboratory mouse.The Mouse Genome Database (MGD) (http://www.informatics.jax.org) is the community model organism database resource for the laboratory mouse, a premier animal model for the study of genetic and genomic systems relevant to human biology and disease. MGD maintains a comprehensive catalog of genes, functional RNAs and other genome features as well as heritable phenotypes and quantitative trait loci. The genome feature catalog is generated by the integration of computational and manual genome annotations generated by NCBI, Ensembl and Vega/HAVANA. MGD curates and maintains the comprehensive listing of functional annotations for mouse genes using the Gene Ontology, and MGD curates and integrates comprehensive phenotype annotations including associations of mouse models with human diseases. Recent improvements include integration of the latest mouse genome build (GRCm38), improved access to comparative and functional annotations for mouse genes with expanded representation of comparative vertebrate genomes and new loads of phenotype data from high-throughput phenotyping projects. All MGD resources are freely available to the research community.2014-01-01T00:00:00Z2014 Jan2024-10-18T05:30:23.217Z2019-03-27T01:23:55ZS-EPMC39649502428530010.1093/nar/gkt1225