{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(4)"],"submitter":["Ge YZ"],"pubmed_abstract":["<h4>Background</h4>Transforming growth factor-beta 1(TGF-β1) is involved in the development of acute rejection (AR) episodes in solid organ transplant recipients; and a number of studies have been conducted to investigate the combined effects of human TGF-β1 gene (TGFB1) +869 T/C and +915 G/C polymorphisms on AR risk. However, the results obtained are inconclusive.<h4>Methods</h4>Eligible studies that investigated the haplotypic association between TGFB1 +869 T/C and +915 G/C polymorphisms and AR risk were comprehensively searched in the PUBMED, EMBASE, China National Knowledge Infrastructure, and Wanfang Database. Statistical analyses were performed by using STATA 12.0 and Review Manager 5.0.<h4>Results</h4>Fourteen eligible studies with 565 AR cases and 1219 non-AR cases were included. O"],"journal":["PloS one"],"pagination":["e93938"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3976347"],"repository":["biostudies-literature"],"pubmed_title":["Combined effects of TGFB1 +869 T/C and +915 G/C polymorphisms on acute rejection risk in solid organ transplant recipients: a systematic review and meta-analysis."],"pmcid":["PMC3976347"],"pubmed_authors":["Zhu XB","Li MH","Jia RP","Gao XF","Li WC","Jiang XM","Ge YZ","Zhu JG","Tan SJ","Song Q","Li LP","Wu R","Lu TZ"],"additional_accession":[]},"is_claimable":false,"name":"Combined effects of TGFB1 +869 T/C and +915 G/C polymorphisms on acute rejection risk in solid organ transplant recipients: a systematic review and meta-analysis.","description":"<h4>Background</h4>Transforming growth factor-beta 1(TGF-β1) is involved in the development of acute rejection (AR) episodes in solid organ transplant recipients; and a number of studies have been conducted to investigate the combined effects of human TGF-β1 gene (TGFB1) +869 T/C and +915 G/C polymorphisms on AR risk. However, the results obtained are inconclusive.<h4>Methods</h4>Eligible studies that investigated the haplotypic association between TGFB1 +869 T/C and +915 G/C polymorphisms and AR risk were comprehensively searched in the PUBMED, EMBASE, China National Knowledge Infrastructure, and Wanfang Database. Statistical analyses were performed by using STATA 12.0 and Review Manager 5.0.<h4>Results</h4>Fourteen eligible studies with 565 AR cases and 1219 non-AR cases were included. O","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014","modification":"2026-05-04T20:49:53.945Z","creation":"2019-03-26T23:25:33Z"},"accession":"S-EPMC3976347","cross_references":{"pubmed":["24705444"],"doi":["10.1371/journal.pone.0093938"]}}