{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Glebov K"],"pubmed_abstract":["<h4>Background</h4>Serotonin (5-HT) is well known as widely distributed modulator of developmental processes in both vertebrates and invertebrates. It is also the earliest neurotransmitter to appear during neuronal development. In aquatic invertebrates, which have larvae in their life cycle, 5-HT is involved in regulation of stages transition including larval metamorphosis and settlement. However, molecular and cellular mechanisms underlying developmental transition in aquatic invertebrate species are yet poorly understood. Earlier we demonstrated that in larvae of freshwater molluscs and marine polychaetes, endogenous 5-HT released from the neurons of the apical sensory organ (ASO) in response to external stimuli retarded larval development at premetamorphic stages, and accelerated it at "],"journal":["BMC developmental biology"],"pagination":["14"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4007640"],"repository":["biostudies-literature"],"pubmed_title":["Mechanisms underlying dual effects of serotonin during development of Helisoma trivolvis (Mollusca)."],"pmcid":["PMC4007640"],"pubmed_authors":["Glebov K","Ivashkin E","Nezlin LP","Ponimaskin EG","Khabarova MY","Voronezhskaya EE"],"additional_accession":[]},"is_claimable":false,"name":"Mechanisms underlying dual effects of serotonin during development of Helisoma trivolvis (Mollusca).","description":"<h4>Background</h4>Serotonin (5-HT) is well known as widely distributed modulator of developmental processes in both vertebrates and invertebrates. It is also the earliest neurotransmitter to appear during neuronal development. In aquatic invertebrates, which have larvae in their life cycle, 5-HT is involved in regulation of stages transition including larval metamorphosis and settlement. However, molecular and cellular mechanisms underlying developmental transition in aquatic invertebrate species are yet poorly understood. Earlier we demonstrated that in larvae of freshwater molluscs and marine polychaetes, endogenous 5-HT released from the neurons of the apical sensory organ (ASO) in response to external stimuli retarded larval development at premetamorphic stages, and accelerated it at ","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Mar","modification":"2026-04-07T16:43:05.777Z","creation":"2026-04-07T15:26:18.596Z"},"accession":"S-EPMC4007640","cross_references":{"pubmed":["24625099"],"doi":["10.1186/1471-213X-14-14"]}}