{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14"],"submitter":["Castro-Pinero J"],"pubmed_abstract":["Background
An objective diagnosis of sedentary behaviour as well as of the physical activity and fitness levels in youth and to better understand how lifestyle is associated with cardiovascular disease risk factors and other phenotypes is of clinical and public health interest, and might be informative for developing intervention studies focused on the promotion of physical activity in these population. The aim of this methodological paper is to describe the design and assessment in the UP&DOWN study.Methods/design
The UP&DOWN study is a multi-center follow-up design where 2225 Spanish primary and secondary schoolchildren from Cadiz and Madrid, respectively, as well as 110 Spanish adolescents with Down syndrome from Madrid and Toledo were recruited to be assessed. Nine main"],"journal":["BMC public health"],"pagination":["400"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4012062"],"repository":["biostudies-literature"],"pubmed_title":["Follow-up in healthy schoolchildren and in adolescents with Down syndrome: psycho-environmental and genetic determinants of physical activity and its impact on fitness, cardiovascular diseases, inflammatory biomarkers and mental health; the UP&DOWN study."],"pmcid":["PMC4012062"],"pubmed_authors":["Gonzalez-Galo A","Alfonso AD","Gheorghe A","Esteban-Cornejo I","Gomez-Gallego F","Castro-Pinero J","Gomez-Martinez S","Cabanas-Sanchez V","Marcos A","Zapatera B","Cordente C","del Rosario Fernandez J","Santiago C","Chillon P","Gavala J","Baeza AC","Acha A","Tejero CM","Villagra H","Carbonell-Baeza A","Veiga OL","Diaz LE","UP&DOWN Study Group","Nova E","Hernandez A","Veses AM","Moledo CP","Guerra GB","Garcia-Cervantes L","Ortega FB","Moya JM","Martinez-Gomez D","Mora-Vicente J","del-Campo J","Gonzalez-Montesinos JL","Galo AG","Izquierdo R","Bandres F","Parrilla F","Ruiz JR","Conde-Caveda J","Mujico JR","Diaz M","Sanz A","Lucia A","Gomez R","Rodriguez-Romo G"],"additional_accession":[]},"is_claimable":false,"name":"Follow-up in healthy schoolchildren and in adolescents with Down syndrome: psycho-environmental and genetic determinants of physical activity and its impact on fitness, cardiovascular diseases, inflammatory biomarkers and mental health; the UP&DOWN study.","description":"Background
An objective diagnosis of sedentary behaviour as well as of the physical activity and fitness levels in youth and to better understand how lifestyle is associated with cardiovascular disease risk factors and other phenotypes is of clinical and public health interest, and might be informative for developing intervention studies focused on the promotion of physical activity in these population. The aim of this methodological paper is to describe the design and assessment in the UP&DOWN study.Methods/design
The UP&DOWN study is a multi-center follow-up design where 2225 Spanish primary and secondary schoolchildren from Cadiz and Madrid, respectively, as well as 110 Spanish adolescents with Down syndrome from Madrid and Toledo were recruited to be assessed. Nine main","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Apr","modification":"2025-04-18T11:32:40.667Z","creation":"2019-03-27T01:27:41Z"},"accession":"S-EPMC4012062","cross_references":{"pubmed":["24761982"],"doi":["10.1186/1471-2458-14-400"]}}