{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(5)"],"submitter":["Bauer A"],"pubmed_abstract":["Membrane envelopment and budding of negative strand RNA viruses (NSVs) is mainly driven by viral matrix proteins (M). In addition, several M proteins are also known to be involved in host cell manipulation. Knowledge about the cellular targets and detailed molecular mechanisms, however, is poor for many M proteins. For instance, Nipah Virus (NiV) M protein trafficking through the nucleus is essential for virus release, but nuclear targets of NiV M remain unknown. To identify cellular interactors of henipavirus M proteins, tagged Hendra Virus (HeV) M proteins were expressed and M-containing protein complexes were isolated and analysed. Presence of acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) in the complex suggested that this protein represents a direct or indirect"],"journal":["PloS one"],"pagination":["e97233"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4019565"],"repository":["biostudies-literature"],"pubmed_title":["ANP32B is a nuclear target of henipavirus M proteins."],"pmcid":["PMC4019565"],"pubmed_authors":["Lamp B","Neumann S","Karger A","Kwasnitschka L","Bauer A","Henning AK","Dietzel E","Balkema-Buschmann A","Finke S","Maisner A","Keil GM"],"additional_accession":[]},"is_claimable":false,"name":"ANP32B is a nuclear target of henipavirus M proteins.","description":"Membrane envelopment and budding of negative strand RNA viruses (NSVs) is mainly driven by viral matrix proteins (M). In addition, several M proteins are also known to be involved in host cell manipulation. Knowledge about the cellular targets and detailed molecular mechanisms, however, is poor for many M proteins. For instance, Nipah Virus (NiV) M protein trafficking through the nucleus is essential for virus release, but nuclear targets of NiV M remain unknown. To identify cellular interactors of henipavirus M proteins, tagged Hendra Virus (HeV) M proteins were expressed and M-containing protein complexes were isolated and analysed. Presence of acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) in the complex suggested that this protein represents a direct or indirect","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014","modification":"2025-04-19T01:31:17.821Z","creation":"2019-06-06T12:44:39Z"},"accession":"S-EPMC4019565","cross_references":{"pubmed":["24823948"],"doi":["10.1371/journal.pone.0097233"]}}