{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["110(10)"],"submitter":["Dalpiaz O"],"pubmed_abstract":["Background
The value of a combined index of neutrophil and white cell counts, named derived neutrophil-lymphocyte ratio (dNLR), has recently been proposed as a prognosticator of survival in various cancer types. We investigated the prognostic role of the dNLR in a large European cohort of patients with upper tract urothelial carcinoma (UTUC).Methods
Data from 171 non-metastatic UTUC patients, operated between 1990 and 2012 at a single tertiary academic centre, were evaluated retrospectively. Cancer-specific- (CSS) as well as overall survival (OS) were assessed using the Kaplan-Meier method. To evaluate the independent prognostic significance of the dNLR, multivariate proportional Cox-regression models were applied. Additionally, the influence of the dNLR on the predictive a"],"journal":["British journal of cancer"],"pagination":["2531-6"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4021523"],"repository":["biostudies-literature"],"pubmed_title":["Validation of the pretreatment derived neutrophil-lymphocyte ratio as a prognostic factor in a European cohort of patients with upper tract urothelial carcinoma."],"pmcid":["PMC4021523"],"pubmed_authors":["Martin Hernandez JM","Zigeuner R","Dalpiaz O","Stojakovic T","Pichler M","Mannweiler S","Hutterer GC","Pummer K"],"additional_accession":[]},"is_claimable":false,"name":"Validation of the pretreatment derived neutrophil-lymphocyte ratio as a prognostic factor in a European cohort of patients with upper tract urothelial carcinoma.","description":"Background
The value of a combined index of neutrophil and white cell counts, named derived neutrophil-lymphocyte ratio (dNLR), has recently been proposed as a prognosticator of survival in various cancer types. We investigated the prognostic role of the dNLR in a large European cohort of patients with upper tract urothelial carcinoma (UTUC).Methods
Data from 171 non-metastatic UTUC patients, operated between 1990 and 2012 at a single tertiary academic centre, were evaluated retrospectively. Cancer-specific- (CSS) as well as overall survival (OS) were assessed using the Kaplan-Meier method. To evaluate the independent prognostic significance of the dNLR, multivariate proportional Cox-regression models were applied. Additionally, the influence of the dNLR on the predictive a","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 May","modification":"2025-04-07T13:02:46.994Z","creation":"2019-03-27T01:28:15Z"},"accession":"S-EPMC4021523","cross_references":{"pubmed":["24691424"],"doi":["10.1038/bjc.2014.180"]}}