{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Matsuzaki M"],"funding":["Economic and Social Research Council","NCATS NIH HHS","Medical Research Council","Wellcome Trust"],"pagination":["1450-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4021785"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["99(6)"],"pubmed_abstract":["<h4>Background</h4>Undernutrition and physical inactivity are both associated with lower bone mass.<h4>Objective</h4>This study aimed to investigate the combined effects of early-life undernutrition and urbanized lifestyles in later life on bone mass accrual in young adults from a rural community in India that is undergoing rapid socioeconomic development.<h4>Design</h4>This was a prospective cohort study of participants of the Hyderabad Nutrition Trial (1987-1990), which offered balanced protein-calorie supplementation to pregnant women and preschool children younger than 6 y in the intervention villages. The 2009-2010 follow-up study collected data on current anthropometric measures, bone mineral density (BMD) measured by dual-energy X-ray absorptiometry, blood samples, diet, physical ac"],"journal":["The American journal of clinical nutrition"],"pubmed_title":["Life-course determinants of bone mass in young adults from a transitional rural community in India: the Andhra Pradesh Children and Parents Study (APCAPS)."],"pmcid":["PMC4021785"],"funding_grant_id":["084674","MC_UU_12013/1","UL1 TR001425","ES/G040923/1"],"pubmed_authors":["Sullivan R","Viljakainen H","Matsuzaki M","Kuper H","Ebrahim S","Kinra S","Kulkarni B","Ben-Shlomo Y","Taylor AE","Davey Smith G","Radhakrishna KV","Ploubidis GB","Prabhakaran D","Tobias JH","Wells JC","Bowen L"],"additional_accession":[]},"is_claimable":false,"name":"Life-course determinants of bone mass in young adults from a transitional rural community in India: the Andhra Pradesh Children and Parents Study (APCAPS).","description":"<h4>Background</h4>Undernutrition and physical inactivity are both associated with lower bone mass.<h4>Objective</h4>This study aimed to investigate the combined effects of early-life undernutrition and urbanized lifestyles in later life on bone mass accrual in young adults from a rural community in India that is undergoing rapid socioeconomic development.<h4>Design</h4>This was a prospective cohort study of participants of the Hyderabad Nutrition Trial (1987-1990), which offered balanced protein-calorie supplementation to pregnant women and preschool children younger than 6 y in the intervention villages. The 2009-2010 follow-up study collected data on current anthropometric measures, bone mineral density (BMD) measured by dual-energy X-ray absorptiometry, blood samples, diet, physical ac","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Jun","modification":"2025-04-19T02:41:04.051Z","creation":"2019-03-27T01:28:16Z"},"accession":"S-EPMC4021785","cross_references":{"pubmed":["24695898"],"doi":["10.3945/ajcn.113.068791"]}}