{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kohn AB"],"funding":["NIDA NIH HHS","NCRR NIH HHS","NIMH NIH HHS","NINDS NIH HHS","NIGMS NIH HHS"],"pagination":["203-7"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4024468"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["63(1)"],"pubmed_abstract":["Ctenophores are one of the most basally branching lineages of metazoans with the largest mitochondrial organelles in the animal kingdom. We sequenced the mitochondrial (mtDNA) genome from the Pacific cidipid ctenophore, Pleurobrachia bachei. The circular mitochondrial genome is 11,016 nts, with only 12 genes, and one of the smallest metazoan mtDNA genomes recorded. The protein coding genes are intronless cox1-3, cob, nad1, 3, 4, 4L and 5. The nad2 and 6 genes are represented as short fragments whereas the atp6 gene was found in the nuclear genome. Only the large ribosomal RNA subunit and two tRNAs were present with possibly the small subunit unidentifiable due to extensive fragmentation. The observed unique features of this mitochondrial genome suggest that nuclear and mitochondrial genome"],"journal":["Molecular phylogenetics and evolution"],"pubmed_title":["Rapid evolution of the compact and unusual mitochondrial genome in the ctenophore, Pleurobrachia bachei."],"pmcid":["PMC4024468"],"funding_grant_id":["R21RR025699","R01 GM097502","R01 MH097062","R01 NS060762","R21 DA030118","5R21DA030118","1R01GM097502","1R01NS060762","R21 RR025699"],"pubmed_authors":["Kocot KM","Halanych KM","Bobkova YV","Citarella MR","Kohn AB","Moroz LL"],"additional_accession":[]},"is_claimable":false,"name":"Rapid evolution of the compact and unusual mitochondrial genome in the ctenophore, Pleurobrachia bachei.","description":"Ctenophores are one of the most basally branching lineages of metazoans with the largest mitochondrial organelles in the animal kingdom. We sequenced the mitochondrial (mtDNA) genome from the Pacific cidipid ctenophore, Pleurobrachia bachei. The circular mitochondrial genome is 11,016 nts, with only 12 genes, and one of the smallest metazoan mtDNA genomes recorded. The protein coding genes are intronless cox1-3, cob, nad1, 3, 4, 4L and 5. The nad2 and 6 genes are represented as short fragments whereas the atp6 gene was found in the nuclear genome. Only the large ribosomal RNA subunit and two tRNAs were present with possibly the small subunit unidentifiable due to extensive fragmentation. The observed unique features of this mitochondrial genome suggest that nuclear and mitochondrial genome","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012 Apr","modification":"2026-04-29T19:01:58.484Z","creation":"2026-04-07T15:28:47.478Z"},"accession":"S-EPMC4024468","cross_references":{"pubmed":["22201557"],"doi":["10.1016/j.ympev.2011.12.009"]}}