{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(5)"],"submitter":["Tho NV"],"pubmed_abstract":["<h4>Background</h4>It is time-consuming to obtain the square root of airway wall area of the hypothetical airway with an internal perimeter of 10 mm (√Aaw at Pi10), a comparable index of airway dimensions in chronic obstructive pulmonary disease (COPD), from all airways of the whole lungs using 3-dimensional computed tomography (CT) analysis. We hypothesized that √Aaw at Pi10 differs among the five lung lobes and √Aaw at Pi10 derived from one certain lung lobe has a high level of agreement with that derived from the whole lungs in smokers.<h4>Methods</h4>Pulmonary function tests and chest volumetric CTs were performed in 157 male smokers (102 COPD, 55 non-COPD). All visible bronchial segments from the 3rd to 5th generations were segmented and measured using commercially available 3-dimensi"],"journal":["PloS one"],"pagination":["e98335"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4035347"],"repository":["biostudies-literature"],"pubmed_title":["Airway wall area derived from 3-dimensional computed tomography analysis differs among lung lobes in male smokers."],"pmcid":["PMC4035347"],"pubmed_authors":["Higami Y","Murakami Y","Ogawa E","Lan le TT","Tho NV","Nakagawa H","Kanda R","Nagao T","Goto K","Oguma T","Seto R","Ryujin Y","Nakano Y","Trang le TH","Fukunaga K","Yamaguchi M"],"additional_accession":[]},"is_claimable":false,"name":"Airway wall area derived from 3-dimensional computed tomography analysis differs among lung lobes in male smokers.","description":"<h4>Background</h4>It is time-consuming to obtain the square root of airway wall area of the hypothetical airway with an internal perimeter of 10 mm (√Aaw at Pi10), a comparable index of airway dimensions in chronic obstructive pulmonary disease (COPD), from all airways of the whole lungs using 3-dimensional computed tomography (CT) analysis. We hypothesized that √Aaw at Pi10 differs among the five lung lobes and √Aaw at Pi10 derived from one certain lung lobe has a high level of agreement with that derived from the whole lungs in smokers.<h4>Methods</h4>Pulmonary function tests and chest volumetric CTs were performed in 157 male smokers (102 COPD, 55 non-COPD). All visible bronchial segments from the 3rd to 5th generations were segmented and measured using commercially available 3-dimensi","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014","modification":"2025-04-22T00:10:51.429Z","creation":"2019-03-26T23:26:06Z"},"accession":"S-EPMC4035347","cross_references":{"pubmed":["24865661"],"doi":["10.1371/journal.pone.0098335"]}}