{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(2)"],"submitter":["Marrachelli VG"],"pubmed_abstract":["To identify factors related with the risk to develop microalbuminuria using combined genomic and metabolomic values from a general population study. One thousand five hundred and two subjects, Caucasian, more than 18 years, representative of the general population, were included. Blood pressure measurement and albumin/creatinine ratio were measured in a urine sample. Using SNPlex, 1251 SNPs potentially associated to urinary albumin excretion (UAE) were analyzed. Serum metabolomic profile was assessed by 1H NMR spectra using a Brucker Advance DRX 600 spectrometer. From the total population, 1217 (mean age 54 ± 19, 50.6% men, ACR>30 mg/g in 81 subjects) with high genotyping call rate were analysed. A characteristic metabolomic profile, which included products from mitochondrial and extra mit"],"journal":["PloS one"],"pagination":["e98227"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4053470"],"repository":["biostudies-literature"],"pubmed_title":["Genomic and metabolomic profile associated to microalbuminuria."],"pmcid":["PMC4053470"],"pubmed_authors":["Mansego ML","Segura R","Chaves FJ","Galan I","Martin-Escudero JC","Marrachelli VG","Marin P","Lliso G","Morales JM","Briongos L","Redon J","Monleon D","Martinez F","Rentero P"],"additional_accession":[]},"is_claimable":false,"name":"Genomic and metabolomic profile associated to microalbuminuria.","description":"To identify factors related with the risk to develop microalbuminuria using combined genomic and metabolomic values from a general population study. One thousand five hundred and two subjects, Caucasian, more than 18 years, representative of the general population, were included. Blood pressure measurement and albumin/creatinine ratio were measured in a urine sample. Using SNPlex, 1251 SNPs potentially associated to urinary albumin excretion (UAE) were analyzed. Serum metabolomic profile was assessed by 1H NMR spectra using a Brucker Advance DRX 600 spectrometer. From the total population, 1217 (mean age 54 ± 19, 50.6% men, ACR>30 mg/g in 81 subjects) with high genotyping call rate were analysed. A characteristic metabolomic profile, which included products from mitochondrial and extra mit","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014","modification":"2026-05-02T20:00:10.556Z","creation":"2019-03-26T23:26:12Z"},"accession":"S-EPMC4053470","cross_references":{"pubmed":["24918908"],"doi":["10.1371/journal.pone.0098227"]}}