{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["27(7)"],"submitter":["Miller PE"],"pubmed_abstract":["<h4>Background</h4>Although a large body of literature has been devoted to examining the relationship between eicosapentaenoic and docosahexaenoic acids (EPA+DHA) and blood pressure, past systematic reviews have been hampered by narrow inclusion criteria and a limited scope of analytical subgroups. In addition, no meta-analysis to date has captured the substantial volume of randomized controlled trials (RCTs) published in the past 2 years. The objective of this meta-analysis was to examine the effect of EPA+DHA, without upper dose limits and including food sources, on blood pressure in RCTs.<h4>Methods</h4>Random-effects meta-analyses were used to generate weighted group mean differences and 95% confidence intervals (CIs) between the EPA+DHA group and the placebo group. Analyses were condu"],"journal":["American journal of hypertension"],"pagination":["885-96"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4054797"],"repository":["biostudies-literature"],"pubmed_title":["Long-chain omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and blood pressure: a meta-analysis of randomized controlled trials."],"pmcid":["PMC4054797"],"pubmed_authors":["Van Elswyk M","Alexander DD","Miller PE"],"additional_accession":[]},"is_claimable":false,"name":"Long-chain omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and blood pressure: a meta-analysis of randomized controlled trials.","description":"<h4>Background</h4>Although a large body of literature has been devoted to examining the relationship between eicosapentaenoic and docosahexaenoic acids (EPA+DHA) and blood pressure, past systematic reviews have been hampered by narrow inclusion criteria and a limited scope of analytical subgroups. In addition, no meta-analysis to date has captured the substantial volume of randomized controlled trials (RCTs) published in the past 2 years. The objective of this meta-analysis was to examine the effect of EPA+DHA, without upper dose limits and including food sources, on blood pressure in RCTs.<h4>Methods</h4>Random-effects meta-analyses were used to generate weighted group mean differences and 95% confidence intervals (CIs) between the EPA+DHA group and the placebo group. Analyses were condu","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Jul","modification":"2025-04-05T10:38:38.716Z","creation":"2019-03-27T01:30:01Z"},"accession":"S-EPMC4054797","cross_references":{"pubmed":["24610882"],"doi":["10.1093/ajh/hpu024"]}}