{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(6)"],"submitter":["Wu Y"],"pubmed_abstract":["<h4>Background</h4>Accumulating evidence suggests that hypoglycaemic agents influence lung cancer risk in patients with diabetes. It remains to be fully elucidated whether conventional hypoglycaemic agents (metformin, sulfonylureas, thiazolidinediones [TZDs] or insulin) affect lung cancer incidence in patients with diabetes.<h4>Methods</h4>We performed a meta-analysis using EMBASE, MEDLINE and Web of Science to search randomised controlled trials (RCTs), cohort studies, and case-control studies published up to October 2013 that assessed the effects of metformin, sulfonylurea, TZDs or insulin on lung cancer risk in subjects with diabetes. Fixed and random effects meta-analysis models were used, and the effect size was expressed as a summary odds ratio (OR) with 95% confidence intervals (CI)"],"journal":["PloS one"],"pagination":["e99577"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4055722"],"repository":["biostudies-literature"],"pubmed_title":["Conventional hypoglycaemic agents and the risk of lung cancer in patients with diabetes: a meta-analysis."],"pmcid":["PMC4055722"],"pubmed_authors":["Shi XF","Wu Y","Liu HB","Song Y"],"additional_accession":[]},"is_claimable":false,"name":"Conventional hypoglycaemic agents and the risk of lung cancer in patients with diabetes: a meta-analysis.","description":"<h4>Background</h4>Accumulating evidence suggests that hypoglycaemic agents influence lung cancer risk in patients with diabetes. It remains to be fully elucidated whether conventional hypoglycaemic agents (metformin, sulfonylureas, thiazolidinediones [TZDs] or insulin) affect lung cancer incidence in patients with diabetes.<h4>Methods</h4>We performed a meta-analysis using EMBASE, MEDLINE and Web of Science to search randomised controlled trials (RCTs), cohort studies, and case-control studies published up to October 2013 that assessed the effects of metformin, sulfonylurea, TZDs or insulin on lung cancer risk in subjects with diabetes. Fixed and random effects meta-analysis models were used, and the effect size was expressed as a summary odds ratio (OR) with 95% confidence intervals (CI)","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014","modification":"2025-04-19T02:39:20.508Z","creation":"2019-03-26T23:26:12Z"},"accession":"S-EPMC4055722","cross_references":{"pubmed":["24924771"],"doi":["10.1371/journal.pone.0099577"]}}