biostudies-literatureUnknown13(4)Zhang Y<h4>Background</h4>Human cytomegalovirus (HCMV) is a virus which has the potential to alter cellular gene expression through multiple mechanisms.<h4>Objective</h4>With the application of DNA microarrays, we could monitor the effects of pathogens on host-cell gene expression programmes in great depth and on a broad scale.<h4>Methods</h4>Changes in mRNA expression levels of human endothelial-like ECV304 cells following infection with human cytomegalovirus AD169 strain was analyzed by a microarray system comprising 21073 60-mer oligonucleotide probes which represent 18716 human genes or transcripts.<h4>Results</h4>The results from cDNA microarray showed that there were 559 differential expressed genes consisted of 471 upregulated genes and 88 down-regulated genes. Real-time qPCR was performedAfrican health sciences864-79https://www.ebi.ac.uk/biostudies/studies/S-EPMC4056481biostudies-literatureErratum: Differential expressed genes in ECV304 Endothelial-like Cells infected with Human Cytomegalovirus.PMC4056481Zheng HZhang YZheng WTu YMo XKe CMa WZhao HfalseErratum: Differential expressed genes in ECV304 Endothelial-like Cells infected with Human Cytomegalovirus.<h4>Background</h4>Human cytomegalovirus (HCMV) is a virus which has the potential to alter cellular gene expression through multiple mechanisms.<h4>Objective</h4>With the application of DNA microarrays, we could monitor the effects of pathogens on host-cell gene expression programmes in great depth and on a broad scale.<h4>Methods</h4>Changes in mRNA expression levels of human endothelial-like ECV304 cells following infection with human cytomegalovirus AD169 strain was analyzed by a microarray system comprising 21073 60-mer oligonucleotide probes which represent 18716 human genes or transcripts.<h4>Results</h4>The results from cDNA microarray showed that there were 559 differential expressed genes consisted of 471 upregulated genes and 88 down-regulated genes. Real-time qPCR was performed2013-01-01T00:00:00Z2013 Dec2025-04-03T22:54:29.645Z2020-05-22T15:16:40ZS-EPMC40564812494030610.4314/ahs.v13i4.2