{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["111(24)"],"submitter":["Chung D"],"pubmed_abstract":["Ethanol is the most widely used renewable transportation biofuel in the United States, with the production of 13.3 billion gallons in 2012 [John UM (2013) Contribution of the Ethanol Industry to the Economy of the United States]. Despite considerable effort to produce fuels from lignocellulosic biomass, chemical pretreatment and the addition of saccharolytic enzymes before microbial bioconversion remain economic barriers to industrial deployment [Lynd LR, et al. (2008) Nat Biotechnol 26(2):169-172]. We began with the thermophilic, anaerobic, cellulolytic bacterium Caldicellulosiruptor bescii, which efficiently uses unpretreated biomass, and engineered it to produce ethanol. Here we report the direct conversion of switchgrass, a nonfood, renewable feedstock, to ethanol without conventional "],"journal":["Proceedings of the National Academy of Sciences of the United States of America"],"pagination":["8931-6"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4066518"],"repository":["biostudies-literature"],"pubmed_title":["Direct conversion of plant biomass to ethanol by engineered Caldicellulosiruptor bescii."],"pmcid":["PMC4066518"],"pubmed_authors":["Chung D","Guss AM","Cha M","Westpheling J"],"additional_accession":[]},"is_claimable":false,"name":"Direct conversion of plant biomass to ethanol by engineered Caldicellulosiruptor bescii.","description":"Ethanol is the most widely used renewable transportation biofuel in the United States, with the production of 13.3 billion gallons in 2012 [John UM (2013) Contribution of the Ethanol Industry to the Economy of the United States]. Despite considerable effort to produce fuels from lignocellulosic biomass, chemical pretreatment and the addition of saccharolytic enzymes before microbial bioconversion remain economic barriers to industrial deployment [Lynd LR, et al. (2008) Nat Biotechnol 26(2):169-172]. We began with the thermophilic, anaerobic, cellulolytic bacterium Caldicellulosiruptor bescii, which efficiently uses unpretreated biomass, and engineered it to produce ethanol. Here we report the direct conversion of switchgrass, a nonfood, renewable feedstock, to ethanol without conventional ","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Jun","modification":"2025-04-21T20:04:08.541Z","creation":"2019-03-27T01:30:36Z"},"accession":"S-EPMC4066518","cross_references":{"pubmed":["24889625"],"doi":["10.1073/pnas.1402210111"]}}