{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8"],"submitter":["Elhalal A"],"pubmed_abstract":["Evidence from neuropsychology and neuroimaging indicate that the pre-frontal cortex (PFC) plays an important role in human memory. Although frontal patients are able to form new memories, these memories appear qualitatively different from those of controls by lacking distinctiveness. Neuroimaging studies of memory indicate activation in the PFC under deep encoding conditions, and under conditions of semantic elaboration. Based on these results, we hypothesize that the PFC enhances memory by extracting differences and commonalities in the studied material. To test this hypothesis, we carried out an experimental investigation to test the relationship between the PFC-dependent factors and semantic factors associated with common and specific features of words. These experiments were performed "],"journal":["Frontiers in human neuroscience"],"pagination":["410"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4073090"],"repository":["biostudies-literature"],"pubmed_title":["The role of the frontal cortex in memory: an investigation of the Von Restorff effect."],"pmcid":["PMC4073090"],"pubmed_authors":["Davelaar EJ","Elhalal A","Usher M"],"additional_accession":[]},"is_claimable":false,"name":"The role of the frontal cortex in memory: an investigation of the Von Restorff effect.","description":"Evidence from neuropsychology and neuroimaging indicate that the pre-frontal cortex (PFC) plays an important role in human memory. Although frontal patients are able to form new memories, these memories appear qualitatively different from those of controls by lacking distinctiveness. Neuroimaging studies of memory indicate activation in the PFC under deep encoding conditions, and under conditions of semantic elaboration. Based on these results, we hypothesize that the PFC enhances memory by extracting differences and commonalities in the studied material. To test this hypothesis, we carried out an experimental investigation to test the relationship between the PFC-dependent factors and semantic factors associated with common and specific features of words. These experiments were performed ","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014","modification":"2026-05-07T07:10:34.858Z","creation":"2025-06-01T00:32:44.339Z"},"accession":"S-EPMC4073090","cross_references":{"pubmed":["25018721"],"doi":["10.3389/fnhum.2014.00410"]}}