{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hutcheon JA"],"funding":["NICHD NIH HHS","CIHR"],"pagination":["701-7"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4095666"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["100(2)"],"pubmed_abstract":["<h4>Background</h4>Current approaches for establishing public health guidelines on the recommended range of weight gain in pregnancy are subjective and nonsystematic.<h4>Objective</h4>In this article, we outline how decision-making on gestational weight-gain guidelines could be aided by quantitative approaches used in noninferiority trials.<h4>Design</h4>We reviewed the theoretical application of noninferiority margins to pregnancy weight-gain guidelines. A worked example illustrated the selection of the recommended range of pregnancy weight gain in women who delivered at the Magee-Womens Hospital, Pittsburgh, PA, in 2003-2010 by identifying weight-gain z scores in which risk of unplanned cesarean delivery, preterm birth, small-for-gestational-age infant, and large-for-gestational-age infa"],"journal":["The American journal of clinical nutrition"],"pubmed_title":["A systematic approach for establishing the range of recommended weight gain in pregnancy."],"pmcid":["PMC4095666"],"funding_grant_id":["R01 HD072008"],"pubmed_authors":["Hutcheon JA","Bodnar LM"],"additional_accession":[]},"is_claimable":false,"name":"A systematic approach for establishing the range of recommended weight gain in pregnancy.","description":"<h4>Background</h4>Current approaches for establishing public health guidelines on the recommended range of weight gain in pregnancy are subjective and nonsystematic.<h4>Objective</h4>In this article, we outline how decision-making on gestational weight-gain guidelines could be aided by quantitative approaches used in noninferiority trials.<h4>Design</h4>We reviewed the theoretical application of noninferiority margins to pregnancy weight-gain guidelines. A worked example illustrated the selection of the recommended range of pregnancy weight gain in women who delivered at the Magee-Womens Hospital, Pittsburgh, PA, in 2003-2010 by identifying weight-gain z scores in which risk of unplanned cesarean delivery, preterm birth, small-for-gestational-age infant, and large-for-gestational-age infa","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Aug","modification":"2025-05-29T20:19:12.428Z","creation":"2025-05-29T20:19:12.428Z"},"accession":"S-EPMC4095666","cross_references":{"pubmed":["24965305"],"doi":["10.3945/ajcn.114.085258"]}}