{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(7)"],"submitter":["Horacio AN"],"pubmed_abstract":["There is limited information on the serotypes causing non-invasive pneumococcal pneumonia (NIPP). Our aim was to characterize pneumococci causing NIPP in adults to determine recent changes in serotype prevalence, the potential coverage of pneumococcal vaccines and changes in antimicrobial resistance. Serotypes and antimicrobial susceptibility profiles of a sample of 1300 isolates recovered from adult patients (≥18 yrs) between 1999 and 2011 (13 years) were determined. Serotype 3 was the most frequent cause of NIPP accounting for 18% of the isolates. The other most common serotypes were 11A (7%), 19F (7%), 19A (5%), 14 (4%), 22F (4%), 23F (4%) and 9N (4%). Between 1999 and 2011, there were significant changes in the proportion of isolates expressing vaccine serotypes, with a steady decline "],"journal":["PloS one"],"pagination":["e103092"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4116175"],"repository":["biostudies-literature"],"pubmed_title":["Non-invasive pneumococcal pneumonia in Portugal--serotype distribution and antimicrobial resistance."],"pmcid":["PMC4116175"],"pubmed_authors":["Sancho L","Alves V","Canas E","Martins F","Cabral C","Chantre O","Iglesias MC","Costa H","Rodrigues M","Pontes C","Daniel I","Peres H","Semedo R","Domingos A","Peres I","Lopes P","Pessanha MA","Rochas H","Marcelo C","Martinho P","Neto O","Reis T","Bento R","Read MA","Fonseca AB","Vieira AP","Hispano P","Portuguese Group for the Study of Streptococcal Infections","Marques T","Silva AC","Nascimento I","Ramirez M","Diaz R","Ribeiro G","Alves A","Ramos MH","Rodrigues A","Ribeiro M","Silva A","Horacio AN","Marrao G","Pinheiro MP","Pinto M","Pina T","Cabral L","Giao M","Raposo E","Tome R","Toscano C","Ramalheira E","Melo-Cristino J","Ferreira T","Morais T","Ribeiro JM","Ferreira R","Canhoto N","Goncalves H","Lito LM","Goncalves E","Boaventura L","Faustino A","Marques J","Bessa F","Afonso MA","Diogo J","Silva MF","Castro AP","Afonso T","Carvalho A","Lopes JP","Felicio L","Vale I","Vaz T","Fontes I","Coutinho A","Grossinho J","Monteiro L","Magalhaes ML","Fonseca F","Tomaz M","Monteiro M","Oliveira H"],"additional_accession":[]},"is_claimable":false,"name":"Non-invasive pneumococcal pneumonia in Portugal--serotype distribution and antimicrobial resistance.","description":"There is limited information on the serotypes causing non-invasive pneumococcal pneumonia (NIPP). Our aim was to characterize pneumococci causing NIPP in adults to determine recent changes in serotype prevalence, the potential coverage of pneumococcal vaccines and changes in antimicrobial resistance. Serotypes and antimicrobial susceptibility profiles of a sample of 1300 isolates recovered from adult patients (≥18 yrs) between 1999 and 2011 (13 years) were determined. Serotype 3 was the most frequent cause of NIPP accounting for 18% of the isolates. The other most common serotypes were 11A (7%), 19F (7%), 19A (5%), 14 (4%), 22F (4%), 23F (4%) and 9N (4%). Between 1999 and 2011, there were significant changes in the proportion of isolates expressing vaccine serotypes, with a steady decline ","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014","modification":"2025-05-29T14:14:19.143Z","creation":"2025-05-29T14:14:19.143Z"},"accession":"S-EPMC4116175","cross_references":{"pubmed":["25075961"],"doi":["10.1371/journal.pone.0103092"]}}