{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2014"],"submitter":["Chua HR"],"pubmed_abstract":["The impact of isoosmolar versus low-osmolar contrast media (CM) administration on contrast-induced acute kidney injury (CI-AKI) and extended renal dysfunction (ERD) is unclear. We retrospectively examined incidences of CI-AKI and ERD in patients who received iodixanol (isoosmolar) versus iohexol (low-osmolar) during angiography for cardiac indications. Of 713 patients, 560 (cohort A), 190 (cohort B), and 172 (cohort C) had serum creatinine monitored at 3 days, 30 days, and 6 months after angiography, respectively. 18% of cohort A developed CI-AKI, which was more common with iodixanol than iohexol (22% versus 13%, P = 0.006). However, patients given iodixanol were older with lower baseline estimated glomerular filtration rates (eGFR). On multivariate analysis, independent associations with "],"journal":["BioMed research international"],"pagination":["506479"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4142278"],"repository":["biostudies-literature"],"pubmed_title":["Extended renal outcomes with use of iodixanol versus iohexol after coronary angiography."],"pmcid":["PMC4142278"],"pubmed_authors":["Bellomo R","Horrigan M","Mcintosh E","Chua HR"],"additional_accession":[]},"is_claimable":false,"name":"Extended renal outcomes with use of iodixanol versus iohexol after coronary angiography.","description":"The impact of isoosmolar versus low-osmolar contrast media (CM) administration on contrast-induced acute kidney injury (CI-AKI) and extended renal dysfunction (ERD) is unclear. We retrospectively examined incidences of CI-AKI and ERD in patients who received iodixanol (isoosmolar) versus iohexol (low-osmolar) during angiography for cardiac indications. Of 713 patients, 560 (cohort A), 190 (cohort B), and 172 (cohort C) had serum creatinine monitored at 3 days, 30 days, and 6 months after angiography, respectively. 18% of cohort A developed CI-AKI, which was more common with iodixanol than iohexol (22% versus 13%, P = 0.006). However, patients given iodixanol were older with lower baseline estimated glomerular filtration rates (eGFR). On multivariate analysis, independent associations with ","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014","modification":"2025-04-26T09:10:08.343Z","creation":"2019-03-27T01:34:34Z"},"accession":"S-EPMC4142278","cross_references":{"pubmed":["25180184"],"doi":["10.1155/2014/506479"]}}