biostudies-literatureUnknown9(8)Garcia-Rio F<h4>Aims</h4>To characterize the distribution of BMI in a population-based sample of COPD patients and to evaluate the impact of obesity on their health status, exercise tolerance, systemic inflammation and comorbidity.<h4>Methods</h4>A population-based sample of 3,797 subjects aged 40-80 years from the EPI-SCAN study was selected. Subjects were categorized according their body mass index (BMI) as underweight (<18.5 kg/m2), normal weight (18.5-24.9 kg/m2), overweight (25.0-29.9 kg/m2) or obese (BMI≥30.0 kg/m2). Subjects were evaluated with post-bronchodilator spirometry and 6-minute walk tests. Smoking habits, respiratory symptoms, generic and specific quality of life, daily physical activities, comorbidities and systemic inflammatory biomarkers were recorded.<h4>Results</h4>The prevalencePloS onee105220https://www.ebi.ac.uk/biostudies/studies/S-EPMC4143213biostudies-literatureImpact of obesity on the clinical profile of a population-based sample with chronic obstructive pulmonary disease.PMC4143213Sobradillo VMunoz LMiravitlles MDuran-Tauleria ESanchez GGarcia-Rio FAncochea JSoriano JBfalseImpact of obesity on the clinical profile of a population-based sample with chronic obstructive pulmonary disease.<h4>Aims</h4>To characterize the distribution of BMI in a population-based sample of COPD patients and to evaluate the impact of obesity on their health status, exercise tolerance, systemic inflammation and comorbidity.<h4>Methods</h4>A population-based sample of 3,797 subjects aged 40-80 years from the EPI-SCAN study was selected. Subjects were categorized according their body mass index (BMI) as underweight (<18.5 kg/m2), normal weight (18.5-24.9 kg/m2), overweight (25.0-29.9 kg/m2) or obese (BMI≥30.0 kg/m2). Subjects were evaluated with post-bronchodilator spirometry and 6-minute walk tests. Smoking habits, respiratory symptoms, generic and specific quality of life, daily physical activities, comorbidities and systemic inflammatory biomarkers were recorded.<h4>Results</h4>The prevalence2014-01-01T00:00:00Z20142025-05-29T22:29:49.254Z2025-05-29T22:29:49.254ZS-EPMC41432132515333110.1371/journal.pone.0105220