biostudies-literature00470Gao FPHS HHSNIGMS NIH HHS10661-4https://www.ebi.ac.uk/biostudies/studies/S-EPMC4148349biostudies-literatureUnknown50(73)An efficient room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl bromides is presented. The Pd(OAc)2/NiXantphos-based catalyst enables the introduction of various aryl and heteroaryl groups, via a deprotonative cross-coupling process (DCCP) in good to excellent yields (60-99%).Chemical communications (Cambridge, England)Room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl and heteroaryl bromides.PMC4148349R01 GM104349104349Walsh PJKim BSGao F47falseRoom-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl and heteroaryl bromides.An efficient room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl bromides is presented. The Pd(OAc)2/NiXantphos-based catalyst enables the introduction of various aryl and heteroaryl groups, via a deprotonative cross-coupling process (DCCP) in good to excellent yields (60-99%).2014-01-01T00:00:00Z2014 Sep2020-11-01T08:43:16Z2019-03-27T01:34:51ZS-EPMC41483492507898810.1039/c4cc05307a