{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bridwell DA"],"funding":["NIBIB NIH HHS","NIMH NIH HHS"],"pagination":["189-94"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4152401"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["158(1-3)"],"pubmed_abstract":["<h4>Background</h4>Individuals with schizophrenia demonstrate deficits in context processing. These deficits can be characterized by examining the influence of auditory context on ERP responses to rare target tones. Previous studies demonstrate that target ERP deficits in schizophrenia depend on the number of non-targets that precede the target ERP. Our goal was to extend these findings by examining whether patients with schizophrenia demonstrate a reduced sensitivity to subtle differences in the auditory context preceding rare target stimuli, as quantified by Itti and Baldi's Bayesian prediction error model.<h4>Methods</h4>Cortical responses to auditory oddball tones were measured within 59 individuals with schizophrenia (SZ) and 59 controls (HC). Individual trial amplitudes were estimate"],"journal":["Schizophrenia research"],"pubmed_title":["Patients with schizophrenia demonstrate reduced cortical sensitivity to auditory oddball regularities."],"pmcid":["PMC4152401"],"funding_grant_id":["MH 1R01077945","R01 EB020407","MH 5R3743775","R01 EB005846","R01 MH077945","1R01EB006841","R01 EB006841"],"pubmed_authors":["Bridwell DA","Kiehl KA","Pearlson GD","Calhoun VD"],"additional_accession":[]},"is_claimable":false,"name":"Patients with schizophrenia demonstrate reduced cortical sensitivity to auditory oddball regularities.","description":"<h4>Background</h4>Individuals with schizophrenia demonstrate deficits in context processing. These deficits can be characterized by examining the influence of auditory context on ERP responses to rare target tones. Previous studies demonstrate that target ERP deficits in schizophrenia depend on the number of non-targets that precede the target ERP. Our goal was to extend these findings by examining whether patients with schizophrenia demonstrate a reduced sensitivity to subtle differences in the auditory context preceding rare target stimuli, as quantified by Itti and Baldi's Bayesian prediction error model.<h4>Methods</h4>Cortical responses to auditory oddball tones were measured within 59 individuals with schizophrenia (SZ) and 59 controls (HC). Individual trial amplitudes were estimate","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Sep","modification":"2025-04-04T10:08:43.385Z","creation":"2019-03-27T01:35:03Z"},"accession":"S-EPMC4152401","cross_references":{"pubmed":["25034764"],"doi":["10.1016/j.schres.2014.06.037"]}}