{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["So H"],"funding":["Basic Energy Sciences","Ministry of Science, ICT and Future Planning","National Research Foundation of Korea","NIGMS NIH HHS"],"pagination":["12229-32"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4156864"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["136(35)"],"pubmed_abstract":["We report the first example of a mononuclear nonheme manganese(III)-hydroperoxo complex derived from protonation of an isolated manganese(III)-peroxo complex bearing an N-tetramethylated cyclam (TMC) ligand, [Mn(III)(TMC)(OOH)](2+). The Mn(III)-hydroperoxo intermediate is characterized with various spectroscopic methods as well as with density functional theory (DFT) calculations, showing the binding of a hydroperoxide ligand in an end-on fashion. The Mn(III)-hydroperoxo species is a competent oxidant in oxygen atom transfer (OAT) reactions, such as the oxidation of sulfides. The electrophilic character of the Mn(III)-hydroperoxo complex is demonstrated unambiguously in the sulfoxidation of para-substituted thioanisoles."],"journal":["Journal of the American Chemical Society"],"pubmed_title":["Spectroscopic characterization and reactivity studies of a mononuclear nonheme Mn(III)-hydroperoxo complex."],"pmcid":["PMC4156864"],"funding_grant_id":["P41 GM103393","NRF-2010-00353","14-BD-0403","2013R1A1A2062737","2013R1A1A2061528","NRF-2012R1A3A2048842","2013K2A2A4000610","2011-0031992"],"pubmed_authors":["So H","Cho J","Lee YM","Park YJ","Sarangi R","Nam W","Cho KB","Seo MS"],"additional_accession":[]},"is_claimable":false,"name":"Spectroscopic characterization and reactivity studies of a mononuclear nonheme Mn(III)-hydroperoxo complex.","description":"We report the first example of a mononuclear nonheme manganese(III)-hydroperoxo complex derived from protonation of an isolated manganese(III)-peroxo complex bearing an N-tetramethylated cyclam (TMC) ligand, [Mn(III)(TMC)(OOH)](2+). The Mn(III)-hydroperoxo intermediate is characterized with various spectroscopic methods as well as with density functional theory (DFT) calculations, showing the binding of a hydroperoxide ligand in an end-on fashion. The Mn(III)-hydroperoxo species is a competent oxidant in oxygen atom transfer (OAT) reactions, such as the oxidation of sulfides. The electrophilic character of the Mn(III)-hydroperoxo complex is demonstrated unambiguously in the sulfoxidation of para-substituted thioanisoles.","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Sep","modification":"2025-04-19T08:53:53.164Z","creation":"2019-03-27T01:35:20Z"},"accession":"S-EPMC4156864","cross_references":{"pubmed":["25116698"],"doi":["10.1021/ja506275q"]}}