{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["31(9)"],"submitter":["Tahmasbpour E"],"pubmed_abstract":["<h4>Background</h4>The assisted reproductive techniques aimed to assist infertile couples have their own offspring carry significant risks of passing on molecular defects to next generations.<h4>Results</h4>Novel breakthroughs in gene and protein interactions have been achieved in the field of male infertility using genome-wide proteomics and transcriptomics technologies.<h4>Conclusion</h4>Male Infertility is a complex and multifactorial disorder.<h4>Significance</h4>This review provides a comprehensive, up-to-date evaluation of the multifactorial factors involved in male infertility. These factors need to be first assessed and understood before we can successfully treat male infertility."],"journal":["Journal of assisted reproduction and genetics"],"pagination":["1115-37"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4156950"],"repository":["biostudies-literature"],"pubmed_title":["A multi-faceted approach to understanding male infertility: gene mutations, molecular defects and assisted reproductive techniques (ART)."],"pmcid":["PMC4156950"],"pubmed_authors":["Agarwal A","Balasubramanian D","Tahmasbpour E"],"additional_accession":[]},"is_claimable":false,"name":"A multi-faceted approach to understanding male infertility: gene mutations, molecular defects and assisted reproductive techniques (ART).","description":"<h4>Background</h4>The assisted reproductive techniques aimed to assist infertile couples have their own offspring carry significant risks of passing on molecular defects to next generations.<h4>Results</h4>Novel breakthroughs in gene and protein interactions have been achieved in the field of male infertility using genome-wide proteomics and transcriptomics technologies.<h4>Conclusion</h4>Male Infertility is a complex and multifactorial disorder.<h4>Significance</h4>This review provides a comprehensive, up-to-date evaluation of the multifactorial factors involved in male infertility. These factors need to be first assessed and understood before we can successfully treat male infertility.","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Sep","modification":"2025-04-04T12:31:46.936Z","creation":"2019-06-06T13:15:01Z"},"accession":"S-EPMC4156950","cross_references":{"pubmed":["25117645"],"doi":["10.1007/s10815-014-0280-6"]}}