biostudies-literatureSeeman MNIA NIH HHSNCRR NIH HHSUniversity of California Los Angeles General Clinical Research CenterNational Institute on Aging143-51https://www.ebi.ac.uk/biostudies/studies/S-EPMC4167677biostudies-literatureUnknown118Data from a national sample of 1255 adults who were part of the MIDUS (Mid-life in the U.S.) follow-up study and agreed to participate in a clinic-based in-depth assessment of their health status were used to test the hypothesis that, quite part from income or educational status, perceptions of lower achieved rank relative to others and of relative inequality in key life domains would be associated with greater evidence of biological health risks (i.e., higher allostatic load). Results indicate that over a variety of status indices (including, for example, the person's sense of control, placement in the community rank hierarchy, perception of inequality in the workplace) a syndrome of perceived relative deprivation is associated with higher levels of biological dysregulation. The evidence Social science & medicine (1982)Social status and biological dysregulation: the "status syndrome" and allostatic load.PMC4167677P01 AG020166P01-AG020166R01-AG033067M01 RR000865R01-AG032271R01 AG032271M01-RR000865R01 AG033067Stein Merkin SKoretz BSeeman TKarlamangla ASeeman MfalseSocial status and biological dysregulation: the "status syndrome" and allostatic load.Data from a national sample of 1255 adults who were part of the MIDUS (Mid-life in the U.S.) follow-up study and agreed to participate in a clinic-based in-depth assessment of their health status were used to test the hypothesis that, quite part from income or educational status, perceptions of lower achieved rank relative to others and of relative inequality in key life domains would be associated with greater evidence of biological health risks (i.e., higher allostatic load). Results indicate that over a variety of status indices (including, for example, the person's sense of control, placement in the community rank hierarchy, perception of inequality in the workplace) a syndrome of perceived relative deprivation is associated with higher levels of biological dysregulation. The evidence 2014-01-01T00:00:00Z2014 Oct2025-04-22T21:06:48.06Z2019-03-27T01:35:53ZS-EPMC41676772511256910.1016/j.socscimed.2014.08.002