{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(10)"],"submitter":["Crabol Y"],"pubmed_abstract":["<h4>Background</h4>Optimal management of eumycetoma, a severely debilitating chronic progressive fungal infection of skin, disseminating to bone and viscera, remains challenging. Especially, optimal antifungal treatment and duration are ill defined.<h4>Methodology/principal findings</h4>We conducted a monocentric retrospective study of 11 imported cases of eumycetoma treated by voriconazole or posaconazole for at least 6 months. Response to treatment was assessed through evolution of clinical and magnetic resonance imaging (MRI). (1→3) ß-D-glucan (BG) and positron emission tomography using [18F] fluorodeoxyglucose (PET/CT) results were also assessed. Identified species were Fusarium solani complex (n = 3); Madurella mycetomatis, (n = 3), and Exophiala jeanselmei, (n = 1). Moreover, two coe"],"journal":["PLoS neglected tropical diseases"],"pagination":["e3232"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4191942"],"repository":["biostudies-literature"],"pubmed_title":["Last generation triazoles for imported eumycetoma in eleven consecutive adults."],"pmcid":["PMC4191942"],"pubmed_authors":["Barete S","Zeller V","Lecuit M","French Mycosis Study Group","Pineau S","Lanternier F","Poiree S","Amazzough K","Maunoury C","Crabol Y","Lortholary O","Bougnoux ME","Arvieux C"],"additional_accession":[]},"is_claimable":false,"name":"Last generation triazoles for imported eumycetoma in eleven consecutive adults.","description":"<h4>Background</h4>Optimal management of eumycetoma, a severely debilitating chronic progressive fungal infection of skin, disseminating to bone and viscera, remains challenging. Especially, optimal antifungal treatment and duration are ill defined.<h4>Methodology/principal findings</h4>We conducted a monocentric retrospective study of 11 imported cases of eumycetoma treated by voriconazole or posaconazole for at least 6 months. Response to treatment was assessed through evolution of clinical and magnetic resonance imaging (MRI). (1→3) ß-D-glucan (BG) and positron emission tomography using [18F] fluorodeoxyglucose (PET/CT) results were also assessed. Identified species were Fusarium solani complex (n = 3); Madurella mycetomatis, (n = 3), and Exophiala jeanselmei, (n = 1). Moreover, two coe","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Oct","modification":"2025-04-03T21:34:16.496Z","creation":"2019-03-26T22:41:15Z"},"accession":"S-EPMC4191942","cross_references":{"pubmed":["25299610"],"doi":["10.1371/journal.pntd.0003232"]}}