biostudies-literatureUnknown8(10)Crabol Y<h4>Background</h4>Optimal management of eumycetoma, a severely debilitating chronic progressive fungal infection of skin, disseminating to bone and viscera, remains challenging. Especially, optimal antifungal treatment and duration are ill defined.<h4>Methodology/principal findings</h4>We conducted a monocentric retrospective study of 11 imported cases of eumycetoma treated by voriconazole or posaconazole for at least 6 months. Response to treatment was assessed through evolution of clinical and magnetic resonance imaging (MRI). (1→3) ß-D-glucan (BG) and positron emission tomography using [18F] fluorodeoxyglucose (PET/CT) results were also assessed. Identified species were Fusarium solani complex (n = 3); Madurella mycetomatis, (n = 3), and Exophiala jeanselmei, (n = 1). Moreover, two coePLoS neglected tropical diseasese3232https://www.ebi.ac.uk/biostudies/studies/S-EPMC4191942biostudies-literatureLast generation triazoles for imported eumycetoma in eleven consecutive adults.PMC4191942Barete SZeller VLecuit MFrench Mycosis Study GroupPineau SLanternier FPoiree SAmazzough KMaunoury CCrabol YLortholary OBougnoux MEArvieux CfalseLast generation triazoles for imported eumycetoma in eleven consecutive adults.<h4>Background</h4>Optimal management of eumycetoma, a severely debilitating chronic progressive fungal infection of skin, disseminating to bone and viscera, remains challenging. Especially, optimal antifungal treatment and duration are ill defined.<h4>Methodology/principal findings</h4>We conducted a monocentric retrospective study of 11 imported cases of eumycetoma treated by voriconazole or posaconazole for at least 6 months. Response to treatment was assessed through evolution of clinical and magnetic resonance imaging (MRI). (1→3) ß-D-glucan (BG) and positron emission tomography using [18F] fluorodeoxyglucose (PET/CT) results were also assessed. Identified species were Fusarium solani complex (n = 3); Madurella mycetomatis, (n = 3), and Exophiala jeanselmei, (n = 1). Moreover, two coe2014-01-01T00:00:00Z2014 Oct2025-04-03T21:34:16.496Z2019-03-26T22:41:15ZS-EPMC41919422529961010.1371/journal.pntd.0003232