{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(11)"],"submitter":["Bohm H"],"pubmed_abstract":["Microbe- or host damage-derived patterns mediate activation of pattern-triggered immunity (PTI) in plants. Microbial virulence factor (effector)-triggered immunity (ETI) constitutes a second layer of plant protection against microbial attack. Various necrosis and ethylene-inducing peptide 1 (Nep1)-like proteins (NLPs) produced by bacterial, oomycete and fungal microbes are phytotoxic virulence factors that exert immunogenic activities through phytotoxin-induced host cell damage. We here show that multiple cytotoxic NLPs also carry a pattern of 20 amino acid residues (nlp20) that triggers immunity-associated plant defenses and immunity to microbial infection in Arabidopsis thaliana and related plant species with similar characteristics as the prototype pattern, bacterial flagellin. Characte"],"journal":["PLoS pathogens"],"pagination":["e1004491"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4223075"],"repository":["biostudies-literature"],"pubmed_title":["A conserved peptide pattern from a widespread microbial virulence factor triggers pattern-induced immunity in Arabidopsis."],"pmcid":["PMC4223075"],"pubmed_authors":["Nurnberger T","Albert I","Oome S","Bohm H","Van den Ackerveken G","Raaymakers TM"],"additional_accession":[]},"is_claimable":false,"name":"A conserved peptide pattern from a widespread microbial virulence factor triggers pattern-induced immunity in Arabidopsis.","description":"Microbe- or host damage-derived patterns mediate activation of pattern-triggered immunity (PTI) in plants. Microbial virulence factor (effector)-triggered immunity (ETI) constitutes a second layer of plant protection against microbial attack. Various necrosis and ethylene-inducing peptide 1 (Nep1)-like proteins (NLPs) produced by bacterial, oomycete and fungal microbes are phytotoxic virulence factors that exert immunogenic activities through phytotoxin-induced host cell damage. We here show that multiple cytotoxic NLPs also carry a pattern of 20 amino acid residues (nlp20) that triggers immunity-associated plant defenses and immunity to microbial infection in Arabidopsis thaliana and related plant species with similar characteristics as the prototype pattern, bacterial flagellin. Characte","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Nov","modification":"2025-04-05T09:46:33.808Z","creation":"2019-03-27T01:39:04Z"},"accession":"S-EPMC4223075","cross_references":{"pubmed":["25375108"],"doi":["10.1371/journal.ppat.1004491"]}}