{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mohamed AD"],"funding":["Wellcome Trust"],"pagination":["e110639"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4229110"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(11)"],"pubmed_abstract":["<h4>Background</h4>Modafinil is a medication licensed for the treatment of narcolepsy. However, it has been reported that healthy individuals without wakefulness disorders are using modafinil off-label to enhance cognitive functioning. Although some studies have reported that modafinil improves cognitive task performance in healthy volunteers, numerous other studies have failed to detect cognitive enhancing effects of modafinil on several well-established neuropsychological tasks. Interestingly, several clinical and preclinical studies have found that improved cognitive task performance by modafinil is accompanied by slower response times. This observation raises the question as to whether this slowing of response time in healthy volunteers is a necessary and sufficient condition for cogni"],"journal":["PloS one"],"pubmed_title":["Modafinil increases the latency of response in the Hayling Sentence Completion Test in healthy volunteers: a randomised controlled trial."],"pmcid":["PMC4229110"],"funding_grant_id":["086041/Z/08/Z"],"pubmed_authors":["Mohamed AD","Lewis CR"],"additional_accession":[]},"is_claimable":false,"name":"Modafinil increases the latency of response in the Hayling Sentence Completion Test in healthy volunteers: a randomised controlled trial.","description":"<h4>Background</h4>Modafinil is a medication licensed for the treatment of narcolepsy. However, it has been reported that healthy individuals without wakefulness disorders are using modafinil off-label to enhance cognitive functioning. Although some studies have reported that modafinil improves cognitive task performance in healthy volunteers, numerous other studies have failed to detect cognitive enhancing effects of modafinil on several well-established neuropsychological tasks. Interestingly, several clinical and preclinical studies have found that improved cognitive task performance by modafinil is accompanied by slower response times. This observation raises the question as to whether this slowing of response time in healthy volunteers is a necessary and sufficient condition for cogni","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014","modification":"2026-04-18T07:28:24.015Z","creation":"2019-03-27T01:39:26Z"},"accession":"S-EPMC4229110","cross_references":{"pubmed":["25391155"],"doi":["10.1371/journal.pone.0110639"]}}