biostudies-literatureBennett TABiotechnology and Biological Sciences Research Council2776-85https://www.ebi.ac.uk/biostudies/studies/S-EPMC4251699biostudies-literatureUnknown24(23)<h4>Background</h4>Plant body plans arise by the activity of meristematic growing tips during development and radiated independently in the gametophyte (n) and sporophyte (2n) stages of the life cycle during evolution. Although auxin and its intercellular transport by PIN family efflux carriers are primary regulators of sporophytic shoot development in flowering plants, the extent of conservation in PIN function within the land plants and the mechanisms regulating bryophyte gametophytic shoot development are largely unknown.<h4>Results</h4>We have found that treating gametophytic shoots of the moss Physcomitrella patens with exogenous auxins and auxin transport inhibitors disrupts apical function and leaf development. Two plasma membrane-targeted PIN proteins are expressed in leafy shoots,Current biology : CBPlasma membrane-targeted PIN proteins drive shoot development in a moss.PMC4251699BB/L002248/1BB/L00224811Bennett TALiu MMBraun MCoudert YDennis RJBierfreund NMReski RWhite CDDecker ELAoyama THarrison CJO'Connor DWang XYfalsePlasma membrane-targeted PIN proteins drive shoot development in a moss.<h4>Background</h4>Plant body plans arise by the activity of meristematic growing tips during development and radiated independently in the gametophyte (n) and sporophyte (2n) stages of the life cycle during evolution. Although auxin and its intercellular transport by PIN family efflux carriers are primary regulators of sporophytic shoot development in flowering plants, the extent of conservation in PIN function within the land plants and the mechanisms regulating bryophyte gametophytic shoot development are largely unknown.<h4>Results</h4>We have found that treating gametophytic shoots of the moss Physcomitrella patens with exogenous auxins and auxin transport inhibitors disrupts apical function and leaf development. Two plasma membrane-targeted PIN proteins are expressed in leafy shoots,2014-01-01T00:00:00Z2014 Dec2026-05-01T04:20:08.061Z2025-06-01T04:00:39.663ZS-EPMC42516992544800310.1016/j.cub.2014.09.054