{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Kumar D"],"pubmed_abstract":["<h4>Background</h4>The R2 repeat region of GLURP has been reported as a good genetic marker for Plasmodium falciparum genotyping. Proper knowledge of the extent and nature of P. falciparum genetic diversity using highly immunogenic R2 repeat region in malaria-endemic areas is a crucial element to understand various aspects related to immunity acquisition and disease pathogenesis.<h4>Methods</h4>Population diversity of P. falciparum GLURP and amino acid sequence repeats in GLURP R2 region was studied in malaria-endemic Assam state, northeast India and compared at an interval of five years during 2005 (Group-A) and 2011 (Group-B).<h4>Results</h4>Of the 66 samples, a total of 55 samples showed positive PCR bands for GLURP R2 region and altogether ten types of alleles with size ranging from 50"],"journal":["Malaria journal"],"pagination":["450"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4256832"],"repository":["biostudies-literature"],"pubmed_title":["Genetic polymorphism and amino acid sequence variation in Plasmodium falciparum GLURP R2 repeat region in Assam, India, at an interval of five years."],"pmcid":["PMC4256832"],"pubmed_authors":["Kumar D","Goswami D","Baruah I","Rabha B","Singh L","Dhiman S","Veer V","Deka M"],"additional_accession":[]},"is_claimable":false,"name":"Genetic polymorphism and amino acid sequence variation in Plasmodium falciparum GLURP R2 repeat region in Assam, India, at an interval of five years.","description":"<h4>Background</h4>The R2 repeat region of GLURP has been reported as a good genetic marker for Plasmodium falciparum genotyping. Proper knowledge of the extent and nature of P. falciparum genetic diversity using highly immunogenic R2 repeat region in malaria-endemic areas is a crucial element to understand various aspects related to immunity acquisition and disease pathogenesis.<h4>Methods</h4>Population diversity of P. falciparum GLURP and amino acid sequence repeats in GLURP R2 region was studied in malaria-endemic Assam state, northeast India and compared at an interval of five years during 2005 (Group-A) and 2011 (Group-B).<h4>Results</h4>Of the 66 samples, a total of 55 samples showed positive PCR bands for GLURP R2 region and altogether ten types of alleles with size ranging from 50","dates":{"release":"2014-01-01T00:00:00Z","publication":"2014 Nov","modification":"2026-05-02T19:58:47.407Z","creation":"2019-03-27T01:41:06Z"},"accession":"S-EPMC4256832","cross_references":{"pubmed":["25416405"],"doi":["10.1186/1475-2875-13-450"]}}