biostudies-literatureUnknown4(4)Geifman NIncreasing efforts are being dedicated towards improving cancer care via personalized medicine. These efforts depend to a large degree on the availability of a knowledge foundation. Unfortunately, existing knowledge linking cancer drugs and potential efficacy biomarkers is in its infancy; and where links are known, they are frequently unstructured and poorly documented. We have developed a new open-access knowledgebase for precision cancer medicine (the PCM Wiki and Knowledgebase). This knowledgebase was constructed using an innovative, two-pronged approach involving a structured knowledgebase at the back-end, and an intuitive knowledge-sharing interface and user-friendly query engine in front. The knowledgebase was seeded with several patient case reports and information was mined via texJournal of personalized medicine475-88https://www.ebi.ac.uk/biostudies/studies/S-EPMC4282884biostudies-literaturePromoting Precision Cancer Medicine through a Community-Driven Knowledgebase.PMC4282884Haviv IKurzrock RRubin EGeifman NfalsePromoting Precision Cancer Medicine through a Community-Driven Knowledgebase.Increasing efforts are being dedicated towards improving cancer care via personalized medicine. These efforts depend to a large degree on the availability of a knowledge foundation. Unfortunately, existing knowledge linking cancer drugs and potential efficacy biomarkers is in its infancy; and where links are known, they are frequently unstructured and poorly documented. We have developed a new open-access knowledgebase for precision cancer medicine (the PCM Wiki and Knowledgebase). This knowledgebase was constructed using an innovative, two-pronged approach involving a structured knowledgebase at the back-end, and an intuitive knowledge-sharing interface and user-friendly query engine in front. The knowledgebase was seeded with several patient case reports and information was mined via tex2014-01-01T00:00:00Z2014 Dec2025-04-21T16:00:12.278Z2019-03-27T01:42:41ZS-EPMC42828842556345810.3390/jpm4040475