{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Berman HM"],"funding":["NIAID NIH HHS","Medical Research Council","NIGMS NIH HHS"],"pagination":["45-58"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC4285880"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["2(Pt 1)"],"pubmed_abstract":["Structural and functional studies require the development of sophisticated 'Big Data' technologies and software to increase the knowledge derived and ensure reproducibility of the data. This paper presents summaries of the Structural Biology Knowledge Base, the VIPERdb Virus Structure Database, evaluation of homology modeling by the Protein Model Portal, the ProSMART tool for conformation-independent structure comparison, the LabDB 'super' laboratory information management system and the Cambridge Structural Database. These techniques and technologies represent important tools for the transformation of crystallographic data into knowledge and information, in an effort to address the problem of non-reproducibility of experimental results."],"journal":["IUCrJ"],"pubmed_title":["Data to knowledge: how to get meaning from your result."],"pmcid":["PMC4285880"],"funding_grant_id":["R01 GM053163","HHSN272201200026C","MC_UP_A025_1012","U01 GM093324","U54 GM094662","U54 GM094585","U54 GM093342"],"pubmed_authors":["Schwede T","Berman HM","Gabanyi MJ","Murshudov GN","Minor W","Reddy V","Westbrook J","Zimmerman MD","Groom CR","Johnson JE","Nicholls RA"],"additional_accession":[]},"is_claimable":false,"name":"Data to knowledge: how to get meaning from your result.","description":"Structural and functional studies require the development of sophisticated 'Big Data' technologies and software to increase the knowledge derived and ensure reproducibility of the data. This paper presents summaries of the Structural Biology Knowledge Base, the VIPERdb Virus Structure Database, evaluation of homology modeling by the Protein Model Portal, the ProSMART tool for conformation-independent structure comparison, the LabDB 'super' laboratory information management system and the Cambridge Structural Database. These techniques and technologies represent important tools for the transformation of crystallographic data into knowledge and information, in an effort to address the problem of non-reproducibility of experimental results.","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Jan","modification":"2025-04-04T09:32:20.912Z","creation":"2019-03-26T22:32:45Z"},"accession":"S-EPMC4285880","cross_references":{"pubmed":["25610627"],"doi":["10.1107/S2052252514023306"]}}