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The platform needed to be relatively affordable, rapid to deploy, and use a common and accessible technology. Central to this project, we wanted to make the content of the platform open to any investigator without restriction. In designing this array we prioritized a number of types of genetic variability for inclusion, such as known risk alleles, disease-causing mutations, putative risk alleles, and other functionally important variants. The array was primarily designed to allow rapid screening of samples for disease-causing mutations and large population studies of risk factors.","dates":{"release":"2015-01-01T00:00:00Z","publication":"2015 Mar","modification":"2026-05-03T05:33:02.808Z","creation":"2019-03-27T01:44:38Z"},"accession":"S-EPMC4317375","cross_references":{"pubmed":["25444595"],"doi":["10.1016/j.neurobiolaging.2014.07.028"]}}