biostudies-literatureFu PNational Cancer InstituteNCI NIH HHSWelch Foundation5656-9https://www.ebi.ac.uk/biostudies/studies/S-EPMC4334230biostudies-literatureUnknown16(21)Inducamides A-C (1-3), three new chlorinated alkaloids featuring an amide skeleton generated by a tryptophan fragment and a 6-methylsalicylic acid unit, were isolated from a chemically induced mutant strain of Streptomyces sp. with the inducamides only being produced in the mutant strain. Their structures, including stereochemistry, were determined by spectroscopic analysis, Marfey's method, and CD spectroscopy.Organic lettersInducamides A-C, chlorinated alkaloids from an RNA polymerase mutant strain of Streptomyces sp.PMC4334230R01 CA149833R01CA1499833I-1689MacMillan JBJamison MLa SFu PfalseInducamides A-C, chlorinated alkaloids from an RNA polymerase mutant strain of Streptomyces sp.Inducamides A-C (1-3), three new chlorinated alkaloids featuring an amide skeleton generated by a tryptophan fragment and a 6-methylsalicylic acid unit, were isolated from a chemically induced mutant strain of Streptomyces sp. with the inducamides only being produced in the mutant strain. Their structures, including stereochemistry, were determined by spectroscopic analysis, Marfey's method, and CD spectroscopy.2014-01-01T00:00:00Z2014 Nov2024-11-08T14:06:26.03Z2019-03-27T01:46:44ZS-EPMC43342302533800610.1021/ol502731p